2 documents found, page 1 of 1
Optical coherence tomography in coronary atherosclerosis assessment and interve...
Araki, Makoto; Park, Seung-Jung; Dauerman, Harold L.; Uemura, Shiro; Kim, Jung-Sun; Di Mario, Carlo; Johnson, Thomas W.; Guagliumi, GiulioSince optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque...
Macrophage skewing by Phd2 haplodeficiency prevents ischemia by inducing arteri...
Takeda, Yukiji; Costa, Sandra Maria Araújo da; Delamarre, Estelle; Roncal, Carmen; Oliveira, Rodrigo Leite de; Squadrito, Mario LeonardoPHD2 serves as an oxygen sensor that rescues blood supply by regulating vessel formation and shape in case of oxygen shortage. However, it is unknown whether PHD2 can influence arteriogenesis. Here we studied the role of PHD2 in collateral artery growth by using hindlimb ischaemia as a model, a process that compensates for the lack of blood flow in case of major arterial occlusion. We show that Phd2 (also known...