6 documents found, page 1 of 1

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Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colo...

Silva, Suellen Laila Rocha; Baliza, Ingrid R. S.; Dias, Rosane Borges; Sales, Caroline Brandi Schlaepfer; Rocha, Clarissa Araújo Gurgel

Ru(II)-thymine complex [Ru(PPh3)2(Thy)(bipy)]PF6 (where PPh3 = triphenylphosphine, Thy = thyminate and bipy = 2,2′-bipyridine) is a potent cytotoxic agent with ability to bind to DNA, inducing caspase-mediated apoptosis in leukemia cells. In this study, we investigated the mechanism underlying the cell death induction by Ru(II)-thymine complex in human colon carcinoma HCT116 cells, as well as its effect in xeno...

Date: 2020   |   Origin: Oasisbr

Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell prol...

Bomfim, Larissa Mendes; Araujo, Fênix Alexandra de; Dias, Rosane Borges; Sales, Caroline Brandi Schlaepfer; Rocha, Clarissa Araújo Gurgel

Ruthenium(II) complexes with 6-methyl-2-thiouracil cis-[Ru(6m2tu)2(PPh3)2] (1) and [Ru(6m2tu)2(dppb)] (2) (where PPh3 = triphenylphosphine; dppb = 1,4-bis(diphenylphosphino)butane; and 6m2tu = 6-methyl-2-thiouracil) are potent cytotoxic agents and able to bind DNA. The aim of this study was to evaluate in vitro cellular underlying mechanism and in vivo effectiveness of these ruthenium(II) complexes in human acu...

Date: 2020   |   Origin: Oasisbr

Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazo...

Silva, Thiago David dos Santos; Bomfim, Larissa Mendes; Rodrigues, Ana Carolina Borges da Cruz; Dias, Rosane Borges; Sales, Caroline Brandi Schlaepfer

Submitted by Renorbio (renorbioba@ufba.br) on 2018-05-02T18:48:24Z No. of bitstreams: 1 ANTI-LIVER CANCER ACTIVITY IN VITRO AND IN VIVO INDUCED BY 2-PYRIDYL 2,3-THIAZOLE DERIVATIVES.pdf: 2793458 bytes, checksum: fcbb9a4336522af9d68dd7cdd4ded487 (MD5); Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2018-05-04T14:23:31Z (GMT) No. of bitstreams: 1 ANTI-LIVER CANCER ACTIVITY IN VITRO AND IN VIVO I...

Date: 2018   |   Origin: Oasisbr

Keratocystic odontogenic tumour: An experience in the northeast of Brazil

Mello, Leonardo Araújo; Gurgel, Clarissa Araújo Silva; Ramos, Eduardo Antônio Gonçalves; Souza, Renata Oliveira de; Sales, Caroline Brandi Schlaepfer

p. 291-297; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-01T12:32:36Z No. of bitstreams: 1 Leonardo Araújo Mello.pdf: 272287 bytes, checksum: 8937963d0c0f6a7e8083657644c694b0 (MD5); Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-10-21T15:57:51Z (GMT) No. of bitstreams: 1 Leonardo Araújo Mello.pdf: 272287 bytes, checksum: 8937963d0c0f6a7e8083657644c694b0 (M...

Date: 2014   |   Origin: Oasisbr

Distribution of mast cells in benign odontogenic tumors

Pereira, Francisco de Assis Caldas; Gurgel, larissa Araújo Silva; Ramos, Eduardo Antônio Gonçalves; Vidal, Manuela Torres Andion

Texto completo: acesso restrito. p. 455-461; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-18T12:44:16Z No. of bitstreams: 1 Francisco de Assis Caldas Pereira.pdf: 497469 bytes, checksum: f0e5e156b3146b36315518bd1d630a0f (MD5); Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-10-10T14:23:55Z (GMT) No. of bitstreams: 1 Francisco de Assis Caldas Pereira.pdf: 497469 bytes, ch...

Date: 2014   |   Origin: Oasisbr

Altered expression of cytokeratins in primary, recurrent and syndrome keratocys...

Santos, Jean Nunes dos; Oliveira, Gabriel Queiroz Vasconcelos; Gurgel, Clarissa Araújo Silva; Souza, Renata Oliveira de

Trabalho completo: acesso restrito, p.269–275; Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-07-06T20:23:03Z No. of bitstreams: 1 (112)fulltext.pdf: 332259 bytes, checksum: cabe5a7981bb691f423b52719e8a2f82 (MD5); Made available in DSpace on 2012-07-06T20:23:03Z (GMT). No. of bitstreams: 1 (112)fulltext.pdf: 332259 bytes, checksum: cabe5a7981bb691f423b52719e8a2f82 (MD5) Previous issue date: 2009; Kerato...

Date: 2012   |   Origin: Oasisbr

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