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Eslicarbazepine acetate as monotherapy in clinical practice: Outcomes from Euro...

Holtkamp, M; Delanty, N; Sales, F; Serratosa, J; McMurray, R; Villanueva, V

OBJECTIVES: To assess the effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) monotherapy in clinical practice in Europe. MATERIALS AND METHODS: Euro-Esli was a pooled analysis of 14 European clinical practice studies. Responder rate (≥50% seizure frequency reduction) and seizure freedom rate (seizure freedom at least since prior visit) were assessed after 3, 6 and 12 months of ESL treatment ...


Anti-NMDA receptor encephalitis presenting with total insomnia--a case report

Marques, IB; Teotónio, R; Cunha, C; Bento, C; Sales, F

Fatal insomnia (FI) is the first diagnosis to be considered by most neurologists when approaching a patient presenting with total insomnia followed by personality and cognitive changes, disturbance of alertness, autonomic hyperactivation and movement abnormalities. We report the case of a 30 year-old male patient who presented with total insomnia followed by episodes of psychomotor restlessness resembling anxie...


Malformations in cortical development in patients with epilepsy. Neuroimaging o...

Carvalho, S; Brito, O; Machado, E; Santos, N; Freitas, P M; Bento, C; Santana, I; Sales, F; Martins, F

This article reviews Malformations of Cortical Development (MCD) diagnosed by Magnetic Resonance Imaging (MRI) in a series of patients with epilepsy. This study spans a five year period. The frequency of these malformations was 7.1%. Most of these were focal or multifocal and the most common ones were polymicrogyria (35.3% of the patients), heterotopia (29.4%), and focal cortical dysplasia (29.4%). The frontal ...

Date: 2001   |   Origin: Acta Médica Portuguesa

Malformações do desenvolvimento cortical em doentes com epilepsia: estudo neuro...

Carvalho, S; Brito, O; Machado, E; Santos, N; Melo Freitas, P; Bento, C; Santana, I; Sales, F; Martins, F

This article reviews Malformations of Cortical Development (MCD) diagnosed by Magnetic Resonance Imaging (MRI) in a series of patients with epilepsy. This study spans a five year period. The frequency of these malformations was 7.1%. Most of these were focal or multifocal and the most common ones were polymicrogyria (35.3% of the patients), heterotopia (29.4%), and focal cortical dysplasia (29.4%). The frontal ...


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