Acute chest syndrome (ACS) is a life-threatening complication in sickle cell disease (SCD). Infections are frequently implied and like other viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be a trigger. Additionally, due to their inflammatory status, they are considered a high-risk group for severe coronavirus disease 2019 (COVID-19). Pneumonia and ACS share clinical, laboratory and ra...
Introduction: Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe manifestation of coronavirus disease 2019 (COVID-19). The aim of this study was to describe the characteristics of children with MIS-C admitted to a pediatric tertiary hospital in Portugal.Material and Methods: Observational descriptive study of MIS-C patients admitted between April 2020 and April 2021. Demographic and clin...
Introduction: Coronavirus disease 2019, or COVID-19, in children is usually a mild disease, but severe illness has been reported. Currently, the therapy benefits of antiviral experimental drugs are still uncertain. The main aim of this study is to describe the experience of a level III hospital regarding therapeutic management of hospitalized children with COVID-19 and to characterize clinical features and evol...
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Infectious mononucleosis is one of the major clinical manifestations of Epstein-Barr virus infection. In this syndrome, elevation of liver transaminase levels is common but cholestasis is rare, with few cases described in the literature. We present the case of a 14-year-old female adolescent, admitted to the Emergency Room with fever, odynophagia and cervical adenomegaly. She was treated with amoxicillin and tw...
A Sitosterolémia (OMIM 210250) é uma doença autossómica recessiva rara causada por mutações nos genes ABCG5/ABCG8 que codificam o transportador intestinal e biliar dos esteróis vegetais, com consequente acumulação no sangue e tecidos. Caracteriza-se pela presença de xantomas e aterosclerose prematura. O diagnóstico é feito pela deteção de sitosterol, campesterol e stigmasterol no plasma e confirmado por estudo ...
One of the risks that banks need to manage, in their financial intermediation activities, is liquidity risk. Thus, banks hold reserves for precautionary reasons, in order to keep enough cash to meet their obligations. In this work, we analyze the demand for excess reserves by Euro Area banks, since the change in the framework of the single monetary policy in March 2004. Our main conclusions are that there is a ...