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Irisin: An anti-inflammatory exerkine in aging and redox-mediated comorbidities

Trettel, Caio Dos Santos; Pelozin, Bruno Rocha de Avila; Barros, Marcelo Paes; Bachi, André Luis Lacerda; Braga, Pedro Gabriel Senger

Human beings lead largely sedentary lives. From an evolutionary perspective, such lifestyle is not beneficial to health. Exercise can promote many enabling pathways, particularly through circulating exerkines, to optimize individual health and quality of life. Such benefits might explain the protective effects of exercise against aging and noncommunicable diseases. Nevertheless, the miRNA-mediated molecular mec...


Combined Chair-Based Exercises Improve Functional Fitness, Mental Well-Being, S...

Furtado, Guilherme Eustáquio; Letieri, Rubens Vinícius; Caldo-Silva, Adriana; Trombeta, Joice C. S.; Monteiro, Clara; Rodrigues, Rafael Nogueira

Regular exercise has long been shown to positively impact the immune system responsiveness and improve mental well-being (MWB). However, the putative links between biomarkers of mental health and immune efficiency in exercising subjects have been scarcely investigated. The aim of this study was to verify the effect of a 14-week combined chair-based exercise program (CEP) on salivary steroid hormones and anti-mi...


Emotional Well-Being and Cognitive Function Have Robust Relationship With Physi...

Furtado, Guilherme Eustáquio; Caldo, Adriana; Vieira-Pedrosa, Ana; Letieri, Rubens Vinícius; Hogervorst, Eef; Teixeira, Ana Maria; Ferreira, José Pedro

Frailty associated to core dimensions of psychological well-being (PwB) has appeared as a possible new frailty phenotype named psychological frailty, implying a parallel to physical frailty (PF). Very little is known about the associations between mental well-being, especially emotional, mood, and self-perception dimensions, and the frailty syndrome in institutionalized older populations. The present study aims...


Fragilidade física e desempenho cognitivo em populações idosas, parte I: revisã...

Furtado, Guilherme Eustáquio; Letieri, Rubens Vinícius; Hogervorst, Eef; Teixeira, Ana Botelho; Ferreira, José Pedro

The purpose of present study was to analyze the magnitude of the effect-size in the assessment of the cognitive status of populations over 60 years of age. The search strategy included PubMed, B-on, Ebsco, Ebsco Health, Scielo, Eric, Lilacs and Sportdiscus data bases. Only observational, cohort and cross-sectional studies were included in the meta-analysis. The central descriptors were elderly-frail, older adul...


Study Protocol on Hormonal Mediation of Exercise on Cognition, Stress and Immun...

Teixeira, Ana M.; Ferreira, José Pedro; Hogervorst, Eef; Braga, Margarida Ferreira; Bandelow, Stephan; Rama, Luís; Figueiredo, António

Physical activity (PA) in elders has been shown to have positive effects on a plethora of chronic diseases and to improve immunity, mental health, and cognition. Chronic stress has also been shown to have immuno-suppressive effects and to accelerate immunosenescence. Exercise could be a significant factor in ameliorating the deleterious effects of chronic stress, but variables such as the type, intensity, and f...


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