6 documents found, page 1 of 1
IMPRESS: Impact of Baseline Depression in Multiple Sclerosis Patients Starting ...
Salgado, António; Silva, Ângela; Santos, Ernestina; Flores, Catarina; Lau, RitaIntroduction: Some studies suggest an association between interferon beta (IFNβ) therapies and the development of depression symptoms in multiple sclerosis (MS). This study aimed to evaluate the impact of baseline depression (BLD) on depression score variation at 24 months (m) in MS patients starting treatment with IFNβ-1a. Methods: Multicenter, prospective, observational study in patients recently diagnosed wi...
Modulation of brain structure and motor function by safinamide multimodal actio...
Araújo, Bruna; Campos, Jonas; Silva, Rita Caridade; Pinheiro, Bárbara Mendes; Marques, Raquel; Barata, Sandra; Lima, Rui; Macedo, Joana MartinsTo date, no neuroprotective/disease-modifying strategy has been approved as a Parkinson’s Disease (PD) therapy, because of the‘one-disease-one-target’ view that has been followed. New drug-based therapeutic routes, namely Safinamide, have been introduced as a promising multimodal drug combining dopaminergic and non-dopaminergic (neuroprotective) actions, representing a new potential alternative therapy to preve...
O treino vocal com o uso da faixa elástica e da bola suíça na otimização do ens...
Costa Filho, Moacyr Silva; Lã, Filipa; Sundberg, Johan; Salgado, António; Castro, Marcelo Peduzzi de; Fonseca, Pedro; Costa, Rui1624-1632 p.; Submitted by Adriene Marchiori (adrienemarchiori@yahoo.com.br) on 2017-06-07T12:50:52Z No. of bitstreams: 1 Artigo_ANPPOM_2012_2_MoacyrCostaFilho.pdf: 196173 bytes, checksum: f2c02b8eeae6c0cec4d5ab4517d3eb11 (MD5); Approved for entry into archive by Nilson Nascimento Souza (nilson@ufba.br) on 2017-07-24T11:09:11Z (GMT) No. of bitstreams: 1 Artigo_ANPPOM_2012_2_MoacyrCostaFilho.pdf: 196173 bytes, c...
Stem cells: microenvironment, micro/nanotechnology, and application
Hua Liu; Zhiyong Zhang; Toh, Wei Seong; Ng, Kee Woei; Sant, Shilpa; Salgado, António[Excerpt] Hard tissue damage and loss caused by mechanical trauma, degenerative diseases, infections, tumors, and other diseases exert a profound negative impact on patients’ quality of life and impose a heavy social and economic burden. Currently, tissue engineering is believed to be a promising approach to recover the structural integrity and function of these damaged or diseased hard tissues.[...]
Osteogenesis Imperfecta – Experience of Dona Estefânia’s Hospital Orthopedics’ ...
Escobar, Carlos; Malveiro, Duarte; Salgado, António; Santos, Maria Inês; Lameirão Campagnolo, João; Cassiano Neves, ManuelIntroduction/Aims: Osteogenesis imperfecta (OI) is a genetic disorder characterized by bone fragility and osteopenia. Treatment involves a multidisciplinary approach and aims to improve the quality of life. The authors aimed to describe the characteristics of a sample of children with OI, to evaluate the treatment and clinical outcome before and after therapy. Material and Methods: An observational, longitudina...
Systemic lupus erythematosus: imaging of central nervous system involvement by ...
Carneiro, Eduarda; Reis, Carina; Pinto, Patrícia; Bernardes, J Miguel; Ribeiro Silva, Maria L; Salgado, AntónioPatients with systemic lupus erythematosus (SLE) can develop dysfunction of the central nervous system (CNS) and have several neurologic syndromes with heterogeneous pathogenic mechanisms. The most common neurologic manifestations of SLE are organic mental syndromes, functional psychoses and seizures.We retrospectively reviewed the magnetic resonance imaging (MRI) of SLE patients with CNS involvement followed i...