Made available in DSpace on 2022-04-29T08:47:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-01-01; The validation of a microbiological assay, applying cylinder plate method for determination of the activity of lomefloxacin in coated tablets is described. Using a strain of Bacillus subtilis ATCC 9372 as the test organism, lomefloxacin was measured in concentrations ranging from 2.0 to 8.0 μg/mL. The m...
Made available in DSpace on 2022-04-29T08:47:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-01-01; A microbiological assay applying the cylinder-plate method is described for determination of the activity of cefoxitin sodium in injectables. Using a strain of Staphylococcus epidermidis ATCC 12226 as the test organism, cefoxitin sodium was measured in concentrations ranging from 50.0 to 200.0 μg/mL. Th...
Made available in DSpace on 2022-04-29T08:47:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-01-01; A rapid, accurate, and sensitive high-performance liquid chromatographic (HPLC) method was developed and validated for the determination of ceftazidime in pharmaceuticals. The method validation parameters yielded good results and included range, linearity, precision, accuracy, specificity, and recovery....
Made available in DSpace on 2022-04-29T08:47:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-01-01; A new UV spectrophotometric method was developed for quantitative evaluation of ceftazidime preparations. The UV detector was set at 255 nm. Beer's law is obeyed in the concentration range of 7.0-14.0 μg/mL. The method was found to be selective, linear, accurate, and precise in the specified ranges. Int...
Made available in DSpace on 2022-04-29T08:48:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-01-01; The objective of this work was to evaluate the preservative effectiveness of liquid crystalline systems containing retynil palmitate (RP) by the challenge test (CT) and D-value. A system was developed containing water, silicon glycol copolymer, and polyether functional siloxane with 1% RP added. The ana...
Made available in DSpace on 2022-04-29T09:12:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-01-01; Flucloxacillin (FLU) is a semi-synthetic penicillin active against Gram-positive bacteria such as streptococci and penicilinase-producing staphylococci, including methicillin-susceptible S. aureus. A simple, rapid and reproducible stability-indicating micellar electrokinetic chromatography (MEKC) method...
Made available in DSpace on 2022-04-29T08:35:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-20; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); BACKGROUND: Rifaximin, a semi-synthetic antimicrobial, does not present microbiological method described in official compendia, and there is a lack of literature on this topic. The quality control of antimicrobials is extremely important to ...
Made available in DSpace on 2022-04-28T20:59:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-01-01; A precise, accurate and low cost spectrophotometric method was developed and validated for routine determination of total polyphenols, as pyrogallic acid equivalents, from the percolated and lyophilized extract of Syzygium cumini (L.) Skeels fruits. Validation was assessed experimentally and data were r...
Made available in DSpace on 2022-04-28T21:00:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-10-01; Tests in animals are used as models in toxicological and investigative studies. However, such tests have been considered inhumane because they can cause pain and suffering to experimental animals, while these methods can often be subjective. Protests calling for animal protection have questioned the eff...
Made available in DSpace on 2022-04-29T07:14:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-01-01; A reversed-phase high performance liquid chromatography method was validated for the determination of cefazolin sodium in lyophilized powder for solution for injection to be applied for quality control in pharmaceutical industry. The liquid chromatography method was conducted on a Zorbax Eclipse Plus C1...