3 documents found, page 1 of 1
Anterior fontanelle closure time in 684 healthy Portuguese children
Costa, Ricardo Craveiro; Salgado, Joana Rosmaninho; Oliveira, Daniela; Mendes, Francisca; Silva, Alexandre; Salgado, ManuelIntroduction and Aim: The timing of anterior fontanelle (AF) closure may be a useful marker for early disease detection. However, the few published studies on this topic have reported significant differences in the normal age ranges of AF closure between countries. The aim of this study was to report AF closure time in the Portuguese population during the last two decades.Methods: This was a 21-year retrospecti...
Isolation, characterization, and differentiation of progenitor cells from human...
Santana, Magda M.; Chung, Kuei-Fang; Vukicevic, Vladimir; Salgado, Joana Rosmaninho; Kanczkowski, Waldemar; Cortez, Vera; Hackmann, KlausChromaffin cells, sympathetic neurons of the dorsal ganglia, and the intermediate small intensely fluorescent cells derive from a common neural crest progenitor cell. Contrary to the closely related sympathetic nervous system, within the adult adrenal medulla a subpopulation of undifferentiated progenitor cells persists, and recently, we established a method to isolate and differentiate these progenitor cells f...
Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus...
Sousa-Ferreira, Lígia; Garrido, Manuel Joaquim Marques; Nascimento-Ferreira, Isabel; Nóbrega, Clévio; Carvalho, Ana dos SantosNeuropeptide Y (NPY) produced by arcuate nucleus (ARC) neurons has a strong orexigenic effect on target neurons. Hypothalamic NPY levels undergo wide-ranging oscillations during the circadian cycle and in response to fasting and peripheral hormones (from 0.25 to 10-fold change). The aim of the present study was to evaluate the impact of a moderate long-term modulation of NPY within the ARC neurons on food consu...