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A methodology to generate design allowables of composite laminates using machin...

Furtado, C.; Pereira, L.F.; Tavares, R.P.; Salgado, M.; Otero, F.; Catalanotti, G.; A. Arteiro, A.; Bessa, M.A.; Camanho, P.P.

This work represents the first step towards the application of machine learning techniques in the prediction of statistical design allowables of composite laminates. Building on data generated analytically, four machine algorithms (XGBoost, Random Forests, Gaussian Processes and Artificial Neural Networks) are used to predict the notched strength of composite laminates and their statistical distribution, associ...


Preparation of barley and yeast β-glucan scaffolds by hydrogel foaming: evaluat...

Salgado, M.; Rodríguez-Royo, S.; Reis, R. L.; Cocero, M. J.; Duarte, Ana Rita C.

Porous polymeric materials are studied in tissue engineering, because they can act as support for cell proliferation and as drug delivery vehicles for regeneration of tissues. Hydrogel foaming with supercritical CO2 is a suitable alternative for the creation of these structures, since it avoids the use of organic solvents and high temperature in the processing. In this work, β-glucans were used as raw material...


Preparation of β-glucan scaffolds by hydrogel foaming with supercritical CO2

Salgado, M.; Duarte, Ana Rita C.; Rodríguez-Royo, S.; Reis, R. L.; Cocero, M. J.

New materials and processing techniques are being constantly developed for the production of scaffolds for tissue engineering applications. Traditionally, foaming of polymers with supercritical fluids is one of the procedures used to create porous matrices. However, this technique cannot be applied to hydrophilic polymers which suffer degradation below their melting temperature. Foaming of hydrogels is an alter...


Successful endoscopic closure of gastrocutaneous fistula with an over-the-scope...

Magalhães, K.; Barrias, S.; Rolanda, C.; Salgado, M.; Magalhães, M.; Simões, V.; Pedroto, I.


Juvenile systemic sclerosis: review of 15 patients

Sousa, S.; Fernandes, S.; Estanqueiro, P.; Zilhão, C.; Resende, C.; Ramos, F.; Salgado, M.; Guedes, M.; Gomes, J.; Santos, M.


Anti-Phytophthora cinnamomi activity of Phlomis purpurea plant and root extracts

Neves, D.; Caetano, P.; Oliveira, J. V.; Maia, Cristiana; Sousa, N.; Salgado, M.; Dionisio, L.; Magan, N.; Cravador, A.

Phlomis purpurea (Lamiaceae), found in Quercus suber and Quercus ilex ssp. rotundifolia forest habitats in southern Portugal, is a non-host for the oomycete Phytophthora cinnamomi, the main biotic factor involved in cork oak and holm oak decline in the Iberian Peninsula. The effect of P. purpurea crude ethanol root extract was evaluated in vitro on P. cinnamomi mycelial growth, sporangial production, zoospore r...


Vulvoperineal Crohn's disease responsive to metronidazole

Rosmaninho, A.; Sanches, M.; Salgado, M.; Alves, R.; Selores, M.

Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and...


Caso hematológico: Púrpura Trombocitopénica Idiopática

São Simão, T.; Salgado, M.; Costa, E.; Barbot, J.

The immune thrombocytopenic purpura (ITP) is a controversial disease. The generality of the literature argues that a historical objective clinical examination and a blood count with careful observation of the peripheral blood smear is sufficient for diagnosis. Some cases contradict this belief.


Anemia ferripriva refractária à terapêutica com ferro oral – que etiologias?

Martins, S.; Costa, E.; Ribeiro, L.; Salgado, M.; Couto, C.; Pereira, F.; Barbot, J.

Introdução: Uma anemia ferripriva refractária (AFR) à terapêutica com ferro oral pode colocar questões delicadas em termos de diagnóstico etiológico. O não cumprimento da terapêutica ou a deficiente correcção de eventuais erros alimentares são as causas mais frequentes. No entanto, é importante ponderar outras etiologias como défice de absorção, hemorragia oculta assim como erros de metabolismo do ferro. Object...


Anafilaxia, alimentos e… futebol

Salgado, M.; Martins, S.; Raposo, F.; Morais, M.; Ramalho, H.; Araújo, A.R.

RESUMO Introdução: A anafilaxia induzida pelo exercício dependente de alimentos (AIEDA) é uma patologia rara. Caracteriza-se pelo facto de determinados alimentos causarem reação anafilática apenas quando se segue a prática de exercício físico, sendo o trigo o alergénio alimentar mais implicado. Caso clínico: Adolescente de 14 anos, sexo masculino, observado no hospital por episódio de náuseas, exantema maculo-p...


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