3 documents found, page 1 of 1
Oxidative precipitation synthesis of calcium-doped manganese ferrite nanopartic...
Veloso, Sérgio Rafael Silva; Andrade, Raquel G. D.; Gomes, Valéria; Amorim, Carlos O.; Amaral, Vítor S.; Salgueiriño, Verónica; Coutinho, Paulo J. G.Superparamagnetic nanoparticles are of high interest for therapeutic applications. In this work, nanoparticles of calcium-doped manganese ferrites (CaxMn1−xFe2O4) functionalized with citrate were synthesized through thermally assisted oxidative precipitation in aqueous media. The method provided well dispersed aqueous suspensions of nanoparticles through a one-pot synthesis, in which the temperature and Ca/Mn r...
Tuning the drug multimodal release through a co-assembly strategy based on magn...
Veloso, Sérgio R. S.; Tiryaki, Ecem; Spuch, Carlos; Hilliou, Loic; Amorim, C. O.; Amaral, V. S.; Coutinho, Paulo J. G.; Ferreira, Paula M. T.Self-assembled short peptide-based gels are highly promising drug delivery systems. However, implementing a stimulus often requires screening different structures to obtain gels with suitable properties, and drugs might not be well encapsulated and/or cause undesirable effects on the gel's properties. To overcome this challenge, a new design approach is presented to modulate the release of doxorubicin as a mode...
Impact of citrate and lipid-functionalized magnetic nanoparticles in dehydropep...
Veloso, Sérgio R S; Silva, Joana F G; Hilliou, L.; Moura, Cacilda; Coutinho, Paulo J. G.; Martins, J. A. R.; Testa-Anta, Martín; Salgueiriño, VerónicaCurrently, the nanoparticle functionalization effect on supramolecular peptide-based hydrogels remains undescribed, but is expected to affect the hydrogels' self-assembly and final magnetic gel properties. Herein, two different functionalized nanoparticles: citrate-stabilized (14.4 ± 2.6 nm) and lipid-coated (8.9 ± 2.1 nm) magnetic nanoparticles, were used for the formation of dehydropeptide-based supramolecula...