6 documents found, page 1 of 1
Stability of hybrid versus vaccine immunity against BA.5 infection over 8 months
Malato, João; Ribeiro, Ruy; Fernandes, Eugénia; Leite, Pedro Pinto; Casaca, Pedro; Antunes, Carlos; Fonseca, Valter R; Gomes, MC; Graca, LuisThe coverage of SARS-CoV-2 vaccination in large parts of the world, together with the high number of breakthrough infections, especially following the emergence of Omicron subvariants, makes hybrid immunity (resulting from vaccine and infection) common. Hybrid immunity, particularly after BA.1 or BA.2 infection, confers substantial protection against the BA.5 infection. However, although the waning of protectio...
Controlling the pandemic during the SARS-CoV-2 vaccination rollout
Viana, João; van Dorp, Christiaan H.; Nunes, Ana; Gomes, MC; van Boven, Michiel; Kretzschmar, Mirjam E.; Veldhoen, Marc; Rozhnova, GannaThere is a consensus that mass vaccination against SARS-CoV-2 will ultimately end the COVID-19 pandemic. However, it is not clear when and which control measures can be relaxed during the rollout of vaccination programmes. We investigate relaxation scenarios using an age-structured transmission model that has been fitted to age-specific seroprevalence data, hospital admissions, and projected vaccination coverag...
Determinants of maternal health care and birth outcome in the Dande Health and ...
Rosário, EVN; Gomes, MC; Brito, M; Costa, DObjectives Maternal health care improvement and reduction of maternal and child mortality are priorities of the global health agenda. In Angola, maternal mortality remains high and the risk of pregnancy-related death was 1 in 32 during 2015. This study aims to identify demographic and social factors influencing antenatal care and health facility delivery among women in Dande and to understand their impact on bi...
Digit Ratio (2D:4D) in Newborns: Influences of Prenatal Testosterone and Matern...
Ventura, T; Gomes, MC; Pita, A; Neto, MT; Taylor, AIntroduction: The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fluid (AF). Subjects and methods: Testosterone was assayed in samples of maternal plasma and AF...
Cortisol and Anxiety Response to a Relaxing Intervention on Pregnant Women Awai...
Ventura, T; Gomes, MC; Carreira, TBackground: Stress and anxiety during pregnancy have been associated with premature and low birth weight babies, presumably through fetus over exposion to glucocorticoids. Antenatal stress also seems to have long-term effects upon infant development and adult health. However, medication for stress may carry risks to the expectant mother, therefore the efficacy of nonpharmacological interventions should be inves...
Análise Descritiva de Parturientes e Recém-Nascidos na Maternidade: Hospital Do...
Ventura, T; Gomes, MCEntre 2005 e 2008, registaram-se 8413 nascimentos na maternidade do Hospital Dona Estefânia (HDE), aproximadamente 8% do total nacional no mesmo período. A mortalidade fetal (0,20%) atingiu os objectivos do Plano Nacional de Saúde (PNS) para 2010 e está aos melhores niveis da União Europeia. Contudo, a percentagem média de nascimentos prétermo (8,1%) e de cesarianas (31,9%) situam-se ainda acima das metas estab...