62 documents found, page 1 of 7
Effect of blueberry supplementation on a diet-induced rat model of prediabetes—...
Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; Girão, Henrique; Figueirinha, ArturBlueberries, red fruits enriched in polyphenols and fibers, are envisaged as a promising nutraceutical intervention in a plethora of metabolic diseases. Prediabetes, an intermediate state between normal glucose tolerance and type 2 diabetes, fuels the development of complications, including hepatic steatosis. In previous work, we have demonstrated that blueberry juice (BJ) supplementation benefits glycemic cont...
Effect of Thymbra capitata (L.) Cav. on Inflammation, Senescence and Cell Migra...
Silva, Jorge M. Alves; Pedreiro, Sónia; Cavaleiro, Carlos; Cruz, M. Teresa; Figueirinha, Artur; Salgueiro, LígiaAromatic plants are reported to display pharmacological properties, including anti-aging. This work aims to disclose the anti-aging effect of the essential oil (EO) of Thymbra capitata (L.) Cav., an aromatic and medicinal plant widely used as a spice, as well as of the hydrodistillation residual water (HRW), a discarded by-product of EO hydrodistillation. The phytochemical characterization of EO and HRW was ass...
Vaginal Sheets with Thymbra capitata Essential Oil for the Treatment of Bacteri...
Tomás, Mariana; Sousa, Lúcia G. V.; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, Carlos; Salgueiro, Lígia; Cerca, NunoWe aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...
Advances in the Phytochemical Characterisation and Bioactivities of Salvia aure...
Silva, Jorge Miguel Alves; Maccioni, Delia; Cocco, Emma; Gonçalves, Maria José; Porcedda, Silvia; Piras, Alessandra; Cruz, M. Teresa; Salgueiro, LígiaThe Salvia L. genus (Lamiaceae) is largely used in the pharmaceutical and food industry. Several species of biological relevance are extensively employed in traditional medicine, including Salvia aurea L. (syn. S. africana-lutea L.), which is used as a traditional skin disinfectant and in wounds as a healing remedy; nevertheless, these properties have not been validated yet. The aim of the present study is to c...
Exploiting the Crithmum maritimum L. Aqueous Extracts and Essential Oil as Pote...
Pedreiro, Sónia; Figueirinha, Artur; Cavaleiro, Carlos; Cardoso, Olga; Donato, Maria Manuel; Salgueiro, Lígia; Ramos, FernandoChritmum maritimum, sea fennel, is a facultative halophyte used in salads, soups, and sauces, as well as used to prepare medicinal juices and aqueous extracts (AE) to treat several ailments. Its essential oil (EO) is used as a spice and aromatizing. In this work, the nutritional (crude protein, fiber, lipids, and ashes content) and HPLC-PDA phenolic profiles were determined. Furthermore, the antioxidant potenti...
Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina ...
Silva, Jorge Miguel Alves; Gonçalves, Maria José; Silva, Ana; Cavaleiro, Carlos; Cruz, M. Teresa; Salgueiro, LígiaFungal infections and the accompanying inflammatory responses are associated with great morbidity and mortality due to the frequent relapses triggered by an increased resistance to antifungal agents. Furthermore, this inflammatory state can be exacerbated during inflammaging and cellular senescence. Essential oils (EO) are receiving increasing interest in the field of drug discovery due to their lipophilic natu...
Unveiling the Chemical Composition and Biological Properties of Salvia cacaliif...
Silva, Jorge M. Alves; Cocco, Emma; Piras, Alessandra; Gonçalves, Maria José; Silva, Ana; Falconieri, Danilo; Porcedda, Silvia; Cruz, M. TeresaSalvia is widely recognized for its therapeutic potential. However, the biological relevance of some species remains unknown, namely Salvia cacaliifolia Benth. Therefore, the aim of this study is to unveil the chemical composition and relevant properties to its essential oil (EO). The EO was characterized by GC and GC-MS and its antifungal effect was evaluated according to the CLSI guidelines on dermatophytes a...
Aromatic Plant-Based Functional Foods: A Natural Approach to Manage Cardiovascu...
Zuzarte, Mónica; Girão, Henrique; Salgueiro, LígiaAromatic plants and their essential oils have shown beneficial effects on the cardiovascular system and, therefore, are potential raw materials in the development of functional foods. However, despite their undeniable potential, essential oils present several limitations that need to be addressed, such as stability, poor solubility, undesirable sensory effects, and low bioavailability. The present review provid...
The Chemical Profile, and Antidermatophytic, Anti-Inflammatory, Antioxidant and...
Correia, Edmilson Emanuel Monteiro; Figueirinha, Artur; Rodrigues, Lisa; Pinela, José; Calhelha, Ricardo C.; Barros, Lillian; Fernandes, ChantalWithania chevalieri, endogenous from Cape Verde, is a medicinal plant used in ethnomedicine with a large spectrum of applications, such as treating skin fungal infections caused by dermatophytes. The aim of this work was to chemically characterize the W. chevalieri crude ethanolic extract (WcCEE), and evaluate its bioactivities as antidermatophytic, antioxidant, anti-inflammatory and anticancer, as well as its ...
Vaginal sheets with Thymbra capitata essential oil for the treatment of bacteri...
Tomás, Mariana; Sousa, Lúcia Filipa Guimarães Vieira; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, CarlosWe aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...