Ethnopharmacological relevance Thymus × citriodorus (Pers.) Schreb. is an interspecific hybrid between Thymus pulegioides and Thymus vulgaris, known for its pharmacological activities as diaphoretic, deodorant, antiseptic and disinfectant, the last mostly related with its antimicrobial activity. The folk use of other extracts, as hydrolates, have also been disseminated, as regulators of oily skin with anti-acne...
The COVID-19 pandemic forced a concerted response from health services to lead to a reduction in care activity. It is a strategy to respond to this health problem centered on clinical provision and, simultaneously, on the protection of the community and health professionals. However, the direct and indirect impact on eye care is still unclear. Objective: To characterize the impact of COVID-19 in the complementa...
ABSTRACT - The COVID-19 pandemic forced a concerted response from health services to lead to a reduction in care activity. It is a strategy to respond to this health problem centered on clinical provision and, simultaneously, on the protection of the community and health professionals. However, the direct and indirect impact on eye care is still unclear. Objective: To characterize the impact of COVID-19 in the ...
[Excerpt] Introduction: Bacterial vaginosis (BV) is a common vaginal disorder that affects women in reproductive age. This condition is characterized by a shift in the vaginal microflora from the dominant beneficial Lactobacillus to an overgrowth of strictly and anaerobic bacteria. It is noteworthy that BV involves the presence of multispecies biofilm, mainly composed by Gardnerella spp.. A major issue related ...
Ridolfia segetum (L.) Moris essential oil was obtained by hydrodistillation and analysed by GC and GC-MS. The antioxidant properties were evaluated through the TBARS assay, and the in vitro anti-inflammatory activity was assessed through inhibition of NO production triggered by the Toll-like receptor 4 (TLR4) agonist, lipopolysaccharide (LPS), in mouse macrophages. Assessment of cell viability was made through ...
In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (family Lamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were tested against Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract (essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmania promastigotes viability was assessed using tetr...
Bacterial vaginosis (BV) is the most common gynecological clinical condition in women in reproductive age, and has been associated with an increased risk of development of preterm labor, spontaneous abortion, and several sexually transmitted diseases such as HIV [1]. BV is not only a condition that involves excessive growth of anaerobic microorganisms, but also involves the presence of an adherent biofilm [2]. ...
Salvia officinalis L. (Lamiaceae) is a Mediterranean species, naturalized in many countries. In Jordan, it is used in traditional medicine as antiseptic, antiscabies, antisyphilitic, and anti-inflammatory, being frequently used against skin diseases. This study aimed the assessment of the antifungal and anti-inflammatory potential of its essential oils, and their cytotoxicity on macrophages and keratinocytes. T...
The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Mentha cervinacollected during the flowering and vegetative phases of the plants were investigated by GC and GC-MS. Quantitative differences were observed in the compositions, particularly in the amounts of pulegone (12.9–79.6%) and isomenthone (8.7–77.0%). Antifungal activity of the oils was evaluated by minim...
The essential oils from Piper capense, P. nigrum, P. guineense and P. umbellatum from S. Tomé e Príncipe were investigated for the first time. They were analysed by GC, GC-mass spectrometry and 13C NMR. Monoterpene hydrocarbons were the main group of constituents in three of the samples (P. capense, P. nigrum and P. umbellatum), whereas for the other species (P. guineense) phenylpropanoid derivatives were the m...