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Boosting antimicrobial activity of ciprofloxacin by functionalization of mesopo...

Juan Mora, Blanca de; Filipe, Luís; Forte, Andreia; Santos, Miguel M.; Alves, Celso; Teodoro, Fernando; Pedrosa, Rui; Carrott, Manuela Ribeiro

Mesoporous silica nanoparticles (MSNs) are very promising nanomaterials for treating bacterial infections when combined with pharmaceutical drugs. Herein, we report the preparation of two nanomaterials based on the immobilization of ciprofloxacin in mesoporous silica nanoparticles, either as the counter-ion of the choline derivative cation (MSN-[Ch][Cip]) or via anchoring on the surface of amino-group modified ...

Date: 2021   |   Origin: IC-online
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