8 documents found, page 1 of 1
An Artificial Intelligence Approach to Thrombophilia Risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states, frequently as venous thrombosis. Venous thromboembolism, represented mainly by deep venous thrombosis and pulmonary embolism, is often a chronic illness, associated with high morbidity and mortality. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of treatment or preven...
An Integrated Soft Computing Approach to Hughes Syndrome Risk Assessment
Vilhena, João; Martins, M. Rosário; Vicente, Henrique; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThe AntiPhospholipid Syndrome (APS) is an acquired autoimmune disorder induced by high levels of antiphospholipid antibodies that cause arterial and veins thrombosis, as well as pregnancy-related complications and morbidity, as clinical manifestations. This autoimmune hypercoagulable state, usually known as Hughes syndrome, has severe consequences for the patients, being one of the main causes of thrombotic dis...
An Artificial Intelligence Approach to Thrombophilia Risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states, frequently as venous thrombosis. Venous thromboembolism, represented mainly by deep venous thrombosis and pulmonary embolism, is often a chronic illness, associated with high morbidity and mortality. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of treatment or preven...
Antiphospholipid Syndrome Risk Evaluation
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThe antiphospholipid syndrome is an acquired autoimmune disorder produced by high titers of antiphospholipid antibodies that cause both arterial and veins thrombosis as well as pregnancy-related complications and morbidity, as clinical manifestations. This autoimmune hypercoagulable state, often associated with coronary artery disease and recurrent Acute Myocardium Infraction, has severe consequences for the pa...
A case-based reasoning view of thrombophilia risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states that increase the risk of venous and arterial thromboses. Indeed, venous thromboembolism is often a chronic illness, mainly in deep venous thrombosis and pulmonary embolism, requiring lifelong prevention strategies. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of trea...
A Soft Computing Approach to Acute Coronary Syndrome
Vicente, Henrique; Martins, M. Rosário; Mendes, Teresa; Vilhena, João; Grañeda, José; Gusmão, Rodrigo; Neves, JoséAcute Coronary Syndrome (ACS) is transversal to a broad and heterogeneous set of human beings, and assumed as a serious diagnosis and risk stratification problem. Although one may be faced with or had at his disposition different tools as biomarkers for the diagnosis and prognosis of ACS, they have to be previously evaluated and validated in different scenarios and patient cohorts. Besides ensuring that a diagn...
Artificial Neural Networks in Acute Coronary Syndrome Screening
Martins, M. Rosário; Mendes, Teresa; Grañeda, José; Gusmão, Rodrigo; Vicente, Henrique; Neves, JoséIn Acute Coronary Syndrome (ACS), early use of correct therapy plays a key role in altering the thrombotic process resulting from plaque rupture, thereby minimizing patient sequels. Indeed, current quality improvement efforts in acute cardiovascular care are focused on closing treatment gaps, so more patients receive evidence-based therapies. Beyond ensuring that effective therapies are administered, attention ...
Identifying the first case of Infection by Rickettsia sibirica in Portugal
Barata, Conceição; de Sousa, Rita; Zambujalinho, Alice; Gusmão, Rodrigo; Azevedo, Francisco; Bacelar, FátimaWe report the first isolation of Rickettsia sibirica (mongolotimonae strain) from the blood of a patient in the Alentejo region, Portugal.; Descreve-se o caso clínico de uma doente, que levou ao isolamento, no sangue, do primeiro caso português de Rickettsia sibirica (estirpe mongolotimonae), na região do Alentejo.