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ant(6)-I Genes encoding aminoglycoside O-nucleotidyltransferases are widely spr...

Hormeño, Lorena; Ugarte-Ruiz, María; Palomo, Gonzalo; Borge, Carmen; Florez-Cuadrado, Diego; Vadillo, Santiago; Píriz, Segundo; Domínguez, Lucas

Date: 2018   |   Origin: IC-online

Detection of plasmid mediated colistin resistance (MCR-1) in Escherichia coli a...

Quesada, Alberto; Ugarte-Ruiz, María; Iglesias, M. Rocío; Porrero, M. Concepción; Martínez, Remigio; Florez-Cuadrado, Diego; Campos, Maria J.

Recent findings suggest that use of colistin as a last resort antibiotic is seriously threatened by the rise of a new plasmid mediated mechanism of resistance (MCR-1). This work identifies, for the first time in Southern Europe, the gene mcr-1 in nine strains from farm animals (poultry and swine) corresponding to five Escherichia coli and four Salmonella enterica, amongwhich three belong to serovar Typhimuriuma...

Date: 2016   |   Origin: IC-online

Identification of the main quinolone resistance determinant in Campylobacter je...

Hormeño, Lorena; Palomo, Gonzalo; Ugarte-Ruiz, María; Porrero, M. Concepción; Borge, Carmen; Vadillo, Santiago; Píriz, Segundo; Domínguez, Lucas

Among zoonotic diseases, campylobacteriosis stands out as the major bacterial infection producing human gastroenteritis. Antimicrobial therapy, only recommended in critical cases, is challenged by resistance mechanisms that should be unambiguously detected for achievement of effective treatments. Quinolone (ciprofloxacin) resistance of Campylobacter jejuni and Campylobacter coli, the2main Campylobacter detected...

Date: 2016   |   Origin: IC-online

Detection of QnrB54 and Its Novel Genetic Context in Citrobacter freundii Isola...

Campos, Maria Jorge; Palomo, Gonzalo; Hormeño, Lorena; Rodrigues, Américo; Sánchez-Benito, Rosario; Píriz, Segundo; Quesada, Alberto

LETTER Quinolone resistance in Enterobacteriaceae is mediated by mutations in the quinolone resistance-determining regions (QRDR) of topoisomerase genes and/or by plasmid-mediated quinolone resistance determinants (PMQR) such as the qnr genes encoding pentapeptide repeat proteins (1). The qnrB family is represented by 80 different alleles (http://www.lahey.org/qnrStudies/); most of them originated from Citrobac...

Date: 2015   |   Origin: IC-online

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