5 documents found, page 1 of 1
Unveiling the Toxicity of Fine and Nano-Sized Airborne Particles Generated from...
Bessa, Maria João; Brandão, Fátima; Fokkens, Paul H.B.; Leseman, Daan L.A.C.; Boere, A. John F.; Cassee, Flemming R.; Salmatonidis, ApostolosHigh-energy industrial processes have been associated with particle release into workplace air that can adversely affect workers’ health. The present study assessed the toxicity of incidental fine (PGFP) and nanoparticles (PGNP) emitted from atmospheric plasma (APS) and high-velocity oxy-fuel (HVOF) thermal spraying. Lactate dehydrogenase (LDH) release, 2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate...
Toxicity assessment of industrial engineered and airborne process-generated nan...
Bessa, Maria João; Brandão, Fátima; Fokkens, Paul; Cassee, Flemming R.; Salmatonidis, Apostolos; Viana, Mar; Vulpoi, Adriana; Simon, SimionThe advanced ceramic technology has been pointed out as a potentially relevant case of occupational exposure to nanoparticles (NP). Not only when nanoscale powders are being used for production, but also in the high-temperature processing of ceramic materials there is also a high potential for NP release into the workplace environment. In vitro toxicity of engineered NP (ENP) [antimony tin oxide (Sb2O3•SnO2; AT...
In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Al...
Bessa, Maria João; Brandão, Fátima; Fokkens, Paul H.B.; Leseman, Daan L.A.C.; Boere, A. John F.; Cassee, Flemming R.; Salmatonidis, ApostolosDiverse industries have already incorporated within their production processes engineered nanoparticles (ENP), increasing the potential risk of worker inhalation exposure. In vitro models have been widely used to investigate ENP toxicity. Air-liquid interface (ALI) cell cultures have been emerging as a valuable alternative to submerged cultures as they are more representative of the inhalation exposure to airbo...
In vitro toxicity of ceramic nanoparticles in 3D human airway epithelial cultures
Bessa, Maria João; Brandão, Fátima; Salmatonidis, Apostolos; Vulpoi, Adriana; Viana, Mar; Cassee, Flemming; Fraga, Sónia; Teixeira, João PauloThis study aimed to investigate the in vitro toxicity of engineered (ENP) and airborne ceramic NP in a 3D human bronchial epithelial model (MucilAir™) under air-liquid interface conditions.
Moving towards an advanced method to assess the toxicity of ceramic nanoparticl...
Bessa, Maria João; Brandão, Fátima; Fokkens, Paul; Boere, John; Leseman, Daan; Salmatonidis, Apostolos; Viana, Mar; Cassee, FlemmingThe aim of this study was to investigate the in vitro toxicity of three ceramic nanoparticles in A549 cell line, a primary target during inhalation exposure.