6 documents found, page 1 of 1
Potential of omega-3 and conjugated fatty acids to control microglia inflammato...
Salsinha, A. S.; Socodato, R.; Rodrigues, A.; Vale-Silva, R.; Relvas, J. B.; Pintado, M.; Rodríguez-Alcalá, L. M.High-fat diet-induced obesity detrimentally affects brain function by inducing chronic low-grade inflammation. This neuroinflammation is, at least in part, likely to be mediated by microglia, which are the main immune cell population in the brain. Microglia express a wide range of lipid-sensitive receptors and their activity can be modulated by fatty acids that cross the blood-brain barrier. Here, by combining ...
The role of saturated and polyunsaturated fatty acids in microglia modulation
Salsinha, A. S.; Rodrigues, A.; Socodato, R.; Relvas, J. B.; Rodríguez-Alcalá, L. M.; Pintado, M. E.
Study of inflammation mediated by fatty acids in a microglia cell model - the o...
Salsinha, A. S.; Rodrigues, A.; Socodato, R.; Relvas, J. B.; Rodríguez-Alcalá, L. M.; Pintado, M. E.
Study of inflammation mediated by lipids in a Microglia Cell Model to deepen in...
Salsinha, A. S.; Rodrigues, A.; Socodato, R.; Relvas, J. B.; Rodríguez-Alcalá, L. M.; Pintado, M. E.
Optimization of linoleic acid emulsion preparation to reduce substrate losses a...
Fontes, A. L.; Pimentel, L. L.; Salsinha, A. S.; Cardoso, B.; Andrade, J. C.; Gomes, A. M.; Rodríguez-Alcalá, L. M.
Characterization of potential CLA-producing strains according to LA tolerance
Fontes, A. L.; Pimentel, L. L.; Salsinha, A. S.; Cardoso, B.; Andrade, J. C.; Rodríguez-Alcalá, L. M.; Gomes, A. M.Introduction: Linoleic acid (LA) present in ruminants diet goes through a series of reactions within the rumen, called the biohydrogenation pathway. This pathway ends up converting LA to stearic acid (C18), but several intermediate products are formed, such as conjugated linoleic acid (CLA) isomers, which have been extensively studied for their potential bioactive properties1,2. Different ruminal bacteria are i...