3 documents found, page 1 of 1
Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in S...
Moreno, PM; Ferreira, AR; Salvador, D; Rodrigues, MT; Torrado, M; Carvalho, ED; Tedebark, U; Sousa, MM; Amaral, IF; Wengel, J; Pêgo, APAfter spinal cord injury (SCI), nerve regeneration is severely hampered due to the establishment of a highly inhibitory microenvironment at the injury site, through the contribution of multiple factors. The potential of antisense oligonucleotides (AONs) to modify gene expression at different levels, allowing the regulation of cell survival and cell function, together with the availability of chemically modified...
Ibuprofen-loaded fibrous patches-taming inhibition at the spinal cord injury site
Pires, L; Lopes, C; Salvador, D; Rocha, DN; Pêgo, APIt is now widely accepted that a therapeutic strategy for spinal cord injury (SCI) demands a multi-target approach. Here we propose the use of an easily implantable bilayer polymeric patch based on poly(trimethylene carbonate-co-e-caprolactone) (P(TMC-CL)) that combines physical guidance cues provided by electrospun aligned fibres and the delivery of ibuprofen, as a mean to reduce the inhibitory environment at ...
Effects of energy level in finisher diets and slaughter age of on the performan...
Albuquerque, R de; Faria, DE de; Junqueira, Otto Mack [UNESP]; Salvador, D; Faria Filho, DE de [UNESP]; Rizzo, MFSubmitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:08:09Z No. of bitstreams: 0; Made available in DSpace on 2013-08-22T19:08:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2003-05-01; Made available in DSpace on 2013-09-30T20:13:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2003-05-01; Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20...