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Abnormal phenotypic distribution of regulatory and effector T cells in octogena...

Cruvinel,Wilson de Melo; Mesquita Júnior,Danilo; Araújo,Júlio Antônio Pereira; Samazi,Karina Carvalho; Kállas,Esper Georges; Cendoroglo,Maysa Seabra

SummaryIntroduction:aging is associated with several immunologic changes. Regulatory (Treg) and effector T cells are involved in the pathogenesis of infectious, neoplastic, and autoimmune diseases. Little is known about the effects of aging on the frequency and function of these T cell subpopulations.Methods:peripheral blood mononuclear cells (PBMC) were obtained from 26 young (under 44 years old) and 18 elderl...

Date: 2015   |   Origin: Oasisbr
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