4 documents found, page 1 of 1
Genetic Background and Expression of the New qepA4 Gene Variant Recovered in Cl...
Manageiro, Vera; Félix, David; Jones-Dias, Daniela; Sampaio, Daniel A; Vieira, Luís; Sancho, Luísa; Ferreira, Eugénia; Caniça, ManuelaA new QepA4 variant was detected in an O86:H28 ST156-fimH38 Escherichia coli, showing a multidrug-resistance phenotype. PAβN inhibition ofqepA4-harboring transconjugant resulted in increase of nalidixic acid accumulation. TheqepA4andcatA1genes were clustered in a 26.0-kp contig matching an IncF-type plasmid, and containing a Tn21-type transposon with multiple mobile genetic elements. This QepA variant is worris...
Salmonella Enteritidis Isolate Harboring Multiple Efflux Pumps and Pathogenicit...
Jones-Dias, Daniela; Clemente, Lurdes; Egas, Conceição; Froufe, Hugo; Sampaio, Daniel A; Vieira, Luís; Fookes, Maria; Thomson, Nicholas RBACKGROUND: Salmonella enterica is one of the most important causes of gastrointestinal infection in humans, being the great majority of infections related to the consumption of poultry meat and eggs (Foley and Lynne, 2008; EFSA/ECDC, 2015). In animals, infections caused by serotype Enteritidis are rarely responsible for severe disease with animals frequently becoming asymptomatic carriers, except in the case o...
Draft Genomic Analysis of an Avian Multidrug Resistant Morganella morganii Isol...
Jones-Dias, Daniela; Clemente, Lurdes; Moura, Inês B; Sampaio, Daniel A; Albuquerque, Teresa; Vieira, Luís; Manageiro, Vera; Caniça, ManuelaMorganella morganii is a commensal bacterium and opportunistic pathogen often present in the gut of humans and animals. We report the 4.3 Mbp draft genome sequence of a M. morganii isolated in association with an Escherichia coli from broilers in Portugal that showed macroscopic lesions consistent with colisepticemia. The analysis of the genome matched the multidrug resistance phenotype and enabled the identifi...
NDM-1-producing Providencia stuartii isolates in a Portuguese Hospital
Manageiro, Vera; Ferreira, Eugénia; Rodrigues, João; Sampaio, Daniel A; Vieira, Luís; Pereira, Patrícia; Rodrigues, Paulo; Palos, CarlosObjective: Providencia stuartii is an opportunistic pathogen typically associated with urinary infections, and is intrinsically resistance to a wide range of antibiotics. The main aim of this study was to characterize five carbapenemase (CA) NDM-1-producing P. stuartii isolates obtained during an outbreak detected in a Hospital. Methods: MICs were obtained by the reference microdilution broth method, according ...