Introduction: Identification of well-appearing infants at risk for early-onset sepsis presents an ongoing challenge. Several guidelines advise categorical risk assessment strategies, resulting in excessive laboratory tests, admissions, and antibiotic use. Currently, approaches using multivariate risk assessment or serial clinical observation are gaining ground. The primary objective of this study was to describ...
Introduction: Therapeutic hypothermia (TH) is the standard of care treatment for brain injury following perinatal hypoxia-ischemia in term infants. Accumulated evidence from clinical trials, systematic reviews and continuous experience shows a reduction in both mortality and long-term neurodevelopmental disability. The aim of our study was to: (i) present the 10-year experience of the neonatal intensive care un...
Introduction: Sudden and unexpected postnatal collapse is a rare event with potentially dramatic consequences. Intervention approaches are limited, but hypothermia has been considered after postnatal collapse. The aim of this study was to analyse sudden and unexpected postnatal collapse cases that underwent therapeutic hypothermia in the five Portuguese hypothermia centres. Material and methods: In this multice...
urpose: To compare the optic disc structure and peripapillary retinal function between high myopes with and without glaucoma and to address the differential role of papillary optical coherence tomography angiography (OCT-A) and circumpapillary microperimetry (cpMP) on the diagnosis and prognosis of this patients. Patients and methods: It is a cross-sectional study including 30 high myopic patients (60 eyes), di...
Introduction: Sudden and unexpected postnatal collapse is a rare event with potentially dramatic consequences. Intervention approaches are limited, but hypothermia has been considered after postnatal collapse. The aim of this study was to analyse sudden and unexpected postnatal collapse cases that underwent therapeutic hypothermia in the five Portuguese hypothermia centres.Material and Methods: In this multicen...
Introduction: Therapeutic hypothermia (TH) is the standard of care treatment for brain injury following perinatal hypoxia-ischemia in term infants. Accumulated evidence from clinical trials, systematic reviews and continuous experience shows a reduction in both mortality and long-term neurodevelopmental disability. The aim of our study was to: (i) present the 10-year experience of the neonatal intensive care un...
Introduction: Sudden and unexpected postnatal collapse is a rare event with potentially dramatic consequences. Intervention approaches are limited, but hypothermia has been considered after postnatal collapse. The aim of this study was to analyse sudden and unexpected postnatal collapse cases that underwent therapeutic hypothermia in the five Portuguese hypothermia centres. Material and Methods: In this multice...
Objetivo: Avaliação dos resultados clínicos dos doentes submetidos a CTLD no Serviço de Oftalmologia do Centro Hospitalar do Porto, EPE entre Agosto de 2006 e Agosto de 2014. Material e Métodos: Estudo retrospetivo em que foram incluídos 130 olhos (121 doentes) com diferentes tipos de glaucoma. O follow-up mínimo foi de 3 meses. Definiu-se sucesso cirúrgico relativo como pressão intra-ocular (PIO) < 22 mm Hg ...
Objetivo: Avaliar os resultados clínicos dos doentes com glaucoma secundário à Polineuropatia Amiloidótica Familiar (PAF) submetidos a implante de válvula de Ahmed no Serviço de Oftalmologia do CHP entre Novembro de 2010 e Fevereiro de 2015. Material e Métodos: Estudo retrospetivo de 37 doentes (47 olhos) com o follow-up mínimo de 6 meses. Definiu-se sucesso cirúrgico relativo como pressão intraocular (PIO) ≥6 ...
Introdução: O fenobarbital é um fármaco anticonvulsivante de primeira linha nas convulsões neonatais. No entanto, durante o tratamento com hipotermia induzida, têm vindo a ser levantadas preocupações com os níveis séricos obtidos devido a alterações na farmacocinética. O objetivo do presente estudo foi a avaliação dos níveis de fenobarbital em recém-nascidos tratados com hipotermia após terem sido tratados com ...