28 documents found, page 1 of 3
Synthesis, characterization and antimicrobial effect of Cu(ii) and Zn(ii) compo...
Almeida, Patricia Saraiva Vilas Boas de; Maia, José Roberto da Silveira; Falqueto, Mariana Caliman; Oliveira, Leandro Licursi deCompounds of Cu(II) and Zn(II) with 3-R-1H-1,2,4-triazole-5-amine {R = methyl (mta), phenyl (pta)} were prepared and characterized by infrared spectroscopy (IR), multinuclear NMR (1H, 13C), electronic spectroscopy (UV-VIS), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), microanalyses and melting point. Dimeric, monomeric, and polymeric materials were synthesized in this work. The Zn(...
Kefir reduces the incidence of pre-neoplastic lesions in an animal model for co...
Reis, Sandra Aparecida dos; Conceição, Lisiane Lopes da; Dias, Mariana Moura e; Siqueira, Nathane Paes; Rosa, Damiana DinizThis study aimed to evaluate the effect of regular consumption of milk kefir on the development of pre-neoplastic colonic lesions. Thirty Wistar rats received water (Control group) or milk (Milk group) or kefir (Kefir group) during five weeks. After that, colonic lesions were chemically induced and the treatments continued for more thirteen weeks. The regular consumption of kefir was able to reduce the incidenc...
Antimicrobial and synergistic activity of 2, 2', 4- trihydroxybenzophenone agai...
Aranda, Martha Isabel Realpe; Gómez, Gabriel Andres Tafur; Barros, Mariana de; Santos, Marcelo Henrique dos; Oliveira, Leandro Licursi deIn poultry farming, the spread of bacterial pathogens results in disease outbreaks causing significant economic losses to this industry. Many of these pathogenic bacteria are zoonotic and have a substantial impact on public health. Antimicrobials are essential for the prevention and treatment of these bacterial infections. However, the indiscriminate use of these agents provides favorable conditions for selecti...
Prevalência de conjuntivite adenoviral em clínica oftalmológica no município de...
Rosado-Filho, Euldes Nei; Cardoso, Silvia Almeida; Marçal, Lorena Nacif; Santos, Eliziária Cardoso dos; Silva, Eduardo de Almeida Marques daAvaliar a prevalência de Adenovírus como agente etiológico da conjuntivite, em clínica médica oftalmológica especializada, em Viçosa, Minas Gerais, Brasil. Amostras da secreção conjuntival de 91 pacientes clinicamente diagnosticados com conjuntivite foram submetidos à reação em cadeia da polimerase (PCR), utilizando primers degenerados para a região codificadora do gene da proteína estrutural II. Posteriormente...
Safety evaluation of the antimicrobial peptide bovicin HC5 orally administered ...
Paiva, Aline Dias; Fernandes, Kenner Morais; Dias, Roberto Sousa; Rocha, Alípio dos Santos; Oliveira, Leandro Licursi de; Neves, Clóvis AndradeBovicin HC5 is an antimicrobial peptide that shows a broad spectrum of activity and potential for biotechnological and therapeutic applications. To gain insight about the safety of bovicin HC5 application, the histological and immunostimulatory effects of orally administrated bovicin HC5 to BALB/c mice were evaluated. BALB/c mice were divided into three groups: negative control (NC group); mice given purified b...
Prevalence of vitamin D deficiency and its relationship with factors associated...
Peçanha, Mirna Brito; Freitas, Rodrigo de Barros; Moreira, Tiago Ricardo; Silva, Luiz Sérgio; Oliveira, Leandro Licursi de; Cardoso, Silvia AlmeidaTo determine the prevalence of vitamin D deficiency/insufficiency in children 0-18 years of age with recurrent wheezing and/or asthma residing in the microregion of Viçosa, Minas Gerais, Brazil, and treated at a referral center, and to determine its association with major risk factors for wheezing. A cross-sectional study was performed using a semi-structured questionnaire, which was administered by trained int...
Lactobacillus curvatus UFV-NPAC1 and other lactic acid bacteria isolated from c...
Castilho, Nathália Parma Augusto; Colombo, Monique; Oliveira, Leandro Licursi de; Todorov, Svetoslav Dimitrov; Nero, Luís AugustoBacteriocins produced by lactic acid bacteria (LAB) can be considered as viable alternatives for food safety and quality, once these peptides present antimicrobial activity against foodborne pathogens and spoilage bacteria. Fermented foods, such as artisanal sausages and cured meats, are relevant sources of LAB strains capable of producing novel bacteriocins, with particular interest by the food industry.Three ...
Trifluoromethyl arylamides with antileukemia effect and intracellular inhibitor...
Siqueira, Raoni Pais; Barros, Marcus Vinícius de Andrade; Barbosa, Éverton de Almeida Alves; Onofre, Thiago Souza; Gonçalves, Victor Hugo SousaThe serine/arginine-rich protein kinases (SRPKs) have frequently been found with altered activity in a number of cancers, suggesting they could serve as potential therapeutic targets in oncology. Here we describe the synthesis of a series of twenty-two trifluoromethyl arylamides based on the known SRPKs inhibitor N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)isonicotinamide (SRPIN340) and the evaluation of th...
Infecção experimental em bovinos: cinética da produção de imunoglobulinas IgM e...
Guimarães-Peixoto, Rafaella Paola Meneguete dos; Pinto, Paulo Sérgio de Arruda; Benjamin, Laércio dos Anjos; Oliveira, Leandro Licursi de; Marcon, LucasA cisticercose bovina é uma zoonose que acomete humanos em sua forma adulta (teníase) e em sua forma larvar encontra-se inserida na musculatura de bovinos infectados (cisticercos). Ainda não está totalmente esclarecido como ocorre a resposta imune animal frente a infecção por cisticercos, sendo necessário sua total compreensão para aprimoramento de testes diagnósticos e prevenção da doença. Este trabalho teve o...
Higher plasma lipopolysaccharide concentrations are associated with less favora...
Moreira, Ana Paula Boroni; Alves, Raquel Duarte Moreira; Teixeira, Tatiana Fiche Salles; Macedo, Viviane Silva; Oliveira, Leandro Licursi deLipopolysaccharide (LPS) from the outer membrane of gram-negative bacteria might be an inflammation trigger in adipose tissue. It has recently been proposed that there is a link between adipose tissue distribution and blood LPS. However, the number of studies on this topic is scarce, and further investigation in humans is required. In this study, we explored the association between plasma LPS concentrations and...