7 documents found, page 1 of 1
Operculina macrocarpa: chemical and intestinal motility effect in mice
Paganotte,Daniele Michelin; Sannomiya,Miriam; Rinaldo,Daniel; Vilegas,Wagner; Salgado,Hérida R.N.ABSTRACT Operculina macrocarpa (L.) Urb., Convolvulaceae, is used by the population as a laxative. In this work we described the isolation of the three phenolic acids present in the hydroethanolic extract of the O. macrocarpa roots. The quantification of the caffeic, chlorogenic acids and of the new caffeic dimer in the hydroethanolic and infusion extracts was performed by high-performance liquid chromatography...
Antimicrobial activity of Byrsonima species (Malpighiaceae)
Michelin,Daniele C.; Sannomiya,Miriam; Figueiredo,Maria E.; Rinaldo,Daniel; Santos,Lourdes C. dos; Souza-Brito,Alba R. M.; Vilegas,WagnerByrsonima species, family Malpighiaceae, is popularly known as "murici". There are several properties attributed to the leaves of Byrsonima species including febrifuge, to treat gastrointestinal dysfunctions and skin diseases. In this work, the antimicrobial activity of Byrsonima fagifolia, B. basiloba and B. intermedia extracts obtained from the leaves were evaluated by using the disc-diffusion method. The res...
Triterpenes and antitubercular activity of Byrsonima crassa
Higuchi,Celio Takashi; Pavan,Fernando Rogério; Leite,Clarice Queico Fujimura; Sannomiya,Miriam; Vilegas,Wagner; Leite,Sergio Roberto de AndradeWe evaluated the potential antitubercular activity of triterpenes obtained from leaves and bark of Byrsonima crassa. From chloroform extracts of the leaves, by bioassay-guided fractionation, we obtained mixtures of known triterpenes: α-amyrin, β-amyrin and their acetates, lupeol, oleanolic acid, ursolic acid and α-amyrinone. Tested against Mycobacterium tuberculosis, the triterpenes exhibited minimum inhibitory...
Flavonoids of Lonchocarpus montanus A.M.G. Azevedo and biological activity
Magalhães,Aderbal F.; Tozzi,Ana Maria G.A.; Magalhães,Eva G.; Sannomiya,Miriam; Soriano,Maria del Pilar C.; Perez,Mary A.F.The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation of twenty three compounds chiefly flavonoids of which five (four flavonoids and one benzophenone) are described for the first time. The molecular structures of the new compounds (1-5) were determined through spectral analysis (UV, IR, MS and NMR) as being: 2'-hydroxy-8-(<FONT FACE=Symbol>a,a</FONT>-dimethylallyl)-2...
New flavone from the leaves of Neea theifera (Nyctaginaceae)
Rinaldo,Daniel; Rodrigues,Clenilson M.; Rodrigues,Juliana; Sannomiya,Miriam; Santos,Lourdes C. dos; Vilegas,WagnerNeea theifera Oerst. (Nyctaginaceae) is widely used in Brazilian folk medicine for the treatment of gastric ulcers and inflammation. Phytochemical investigation of the leaves of Neea theifera afforded the isolation of the new flavone luteolin-7-O-[2''-O-(5'''-O-feruloyl)- beta-D-apiofuranosyl]-b-D-glucopyranoside (1) besides the eight-known compounds vitexin, isovitexin, isoorientin, orientin, vicenin-2, chryso...
Preparative separation of flavonoids from the medicinal plant Davilla elliptica...
Rinaldo,Daniel; Silva,Marcelo Aparecido; Rodrigues,Clenilson Martins; Calvo,Tamara Regina; Sannomiya,Miriam; Santos,Lourdes Campaner dos; Vilegas,WagnerHigh-speed counter-current chromatography (HSCCC) is a major tool for the fast separation of natural products from plants. It was used for the preparative isolation of the flavonoid monoglucosides present in the aerial parts of the Davilla elliptica St. Hill. (Dilleniaceae). This species is used in Brazilian folk medicine for the treatment of gastric disorders. The optimum solvent system used was composed of a ...
n-alkanes from Paepalanthus Mart. species (Eriocaulaceae)
Santos,Lourdes Campaner dos; Dokkedal,Anne L.; Sannomiya,Miriam; Soares,Maria Carla Piza; Vilegas,WagnerThis work presents the study of nonpolar compounds from plants belonging to the genus Paepalanthus Mart. (Eriocaulaceae). Long-chain linear aliphatic hydrocarbons were identified by GC-FID and GC-MS. The results indicate that Paepalanthus subg. Platycaulon species present a very homogenous profile, with carbon chains of n-alkanes ranging from C25 to C31, most samples presenting higher frequencies of C27 and C29...