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How should clinical wound care and management translate to effective engineerin...

Gefen, Amit; Alves, Paulo; Beeckman, Dimitri; Cullen, Breda; Lázaro-Martínez, José Luis; Lev-Tov, Hadar; Najafi, Bijan; Santamaria, Nick; Sharpe, Andrew

Significance: Wounds of all types remain one of the most important, expensive, and common medical problems, for example, up to approximately two-thirds of the work time of community nurses is spent on wound management. Many wounds are treated by means of dressings. The materials used in a dressing, their microarchitecture, and how they are composed and constructed form the basis for the laboratory and clinical ...


Fluid handling by foam wound dressings: from engineering theory to advanced lab...

Gefen, Amit; Alves, Paulo; Beeckman, Dimitri; Cullen, Breda; Lázaro-Martínez, José Luis; Lev-Tov, Hadar; Santamaria, Nick; Swanson, Terry; Woo, Kevin

This article describes the contemporary bioengineering theory and practice of evaluating the fluid handling performance of foam-based dressings, with focus on the important and clinically relevant engineering structure– function relationships and on advanced laboratory testing methods for preclinical quantitative assessments of this common type of wound dressings. The effects of key wound dressing material-rela...


Clinical performance characteristics for bordered foam dressings in the treatme...

Santamaria, Nick; Woo, Kevin; Beeckman, Dimitri; Alves, Paulo; Cullen, Breda; Gefen, Amit; Lázaro-Martínez, José Luis; Lev-Tov, Hadar; Najafi, Bijan

The aim of this article is to identify and describe clinical practice performance characteristics for bordered foam dressings in the treatment of complex wounds. Our recently published systematic review of outcomes and applied measurement instruments for the use of bordered foam dressings in complex wounds has led to us identifying a range of important clinical and patient-centred issues related to this dressin...


The development of a core outcome set for clinical effectiveness studies of bor...

Raepsaet, Charlotte; Alves, Paulo; Cullen, Breda; Gefen, Amit; Lázaro-Martínez, José Luis; Lev-Tov, Hadar; Najafi, Bijan; Santamaria, Nick

Aim: The aim of this project was to develop a core outcome set (COS) for clinical effectiveness studies of bordered foam dressings in the treatment of complex wounds. Methods: The research project followed the Core Outcome Measures in Effectiveness Trials (COMET) initiative and consisted of two phases. The first phase prepared the background and process, while the second phase had three steps: outcome list gene...


Clinical and cost effectiveness of a system for turning and positioning intensi...

Kapp, Suzanne; Gerdtz, Marie; Gefen, Amit; Padula, William; Alves, Paulo; Trevellini, Chenel; Ghosh, Angaj; Shea, Ashley; Cross, Anthony; Sousa, Ines

Pressure injuries affect 13.1% to 45.5% of patients in the intensive care unit and lead to pain and discomfort for patients, burden on healthcare providers, and unnecessary cost to the health system. Turning and positioning systems offer improvements on usual care devices, however the evidence of the effectiveness of such systems is still emerging. We conducted an investigator initiated, prospective, single cen...


Study protocol for the development of a core outcome set (COS) for clinical eff...

Raepsaet, Charlotte; Alves, Paulo; Cullen, Breda; Gefen, Amit; Lázaro-Martínez, José Luis; Lev-Tov, Hadar; Najafi, Bijan; Santamaria, Nick


The sorptivity and durability of gelling fibre dressings tested in a simulated ...

Lustig, Adi; Alves, Paulo; Call, Evan; Santamaria, Nick; Gefen, Amit

Wound-dressing performances are affected by exudate viscosity, resistance to flow because of gravity, and bodyweight loads, the level of which is related to the body position. Here, we focussed on two dressing properties: (a) Sorptivity—the ability of dressings to transfer exudate away from the wound bed by capillary action—and (b) Durability—the capacity of dressings to maintain their integrity over time and d...


Prevention and management of pressure injury to the heel

Black, Joyce; Santamaria, Nick; Gefen, Amit; Brindle, Tod; Fletcher, Jacqui; Alves, Paulo

Pressure injuries on the heels often occur in immobile patients. The risk factors for these injuries stem from the anatomy of the calcaneus, impairments in blood flow to the foot and neuropathic disease. There are many clinical considerations in the prevention of heel pressure injury. This article addresses the epidemiology and economic impact of heel injury, identifies risk factors and differential diagnosis o...


Meeting report: pressure injury prevention: clinical outcomes explained by robu...

Alves, Paulo; Creehan, Sue; Gefen, Amit; Santamaria, Nick; Trevellini, Chenel

This meeting report summarises the proceedings of a panel-led symposium that took place at the European Wound Management Association (EWMA) Conference,Amsterdam in May 2017. It looks at the crucial role of pressure injury prevention and the importance of robust clinical data in proving the positive impact — for patients, clinicians and the healthcare economy — of implementing strategies that include the use of ...


Meeting report: Are you doing everything possible to prevent pressure injury th...

Harding, Keith; Black, Joyce; Gefen, Amit; Santamaria, Nick; Alves, Paulo; Ohura, Norihoko; Brindle, Tod; Trevellini, Chenel


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