Objective: to analyze the temporal trend of the incidence of Acquired Immunodeficiency Syndrome (AIDS) in people aged 50 years or more in Brazil and its regions. Method: a mixed ecological study of reported cases of AIDS in people aged 50 years or more between 2007 and 2017, in Brazil and regions. Data were extracted from the National System of Diseases and Notification and analyzed using the Prais-Winsten met...