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Metabolomics as a Tool to Understand Nano-Plant Interactions: The Case Study of...
Silva, Sónia; Dias, Maria Celeste; Pinto, Diana C. G. A.; Silva, Artur M. S.Metabolomics is a powerful tool in diverse research areas, enabling an understanding of the response of organisms, such as plants, to external factors, their resistance and tolerance mechanisms against stressors, the biochemical changes and signals during plant development, and the role of specialized metabolites. Despite its advantages, metabolomics is still underused in areas such as nano-plant interactions. ...
Chemical Composition and Phytopharmaceuticals : An Overview of the Caulerpa and...
Rosa, Gonçalo P.; Barreto, Maria do Carmo; Seca, Ana M. L.; Pinto, Diana C. G. A.In recent years, macroalgae attracted increasing attention from many industries of diverse branches such as plastics, cosmetics, pharmaceuticals, and food. This interest is due to the diverse chemical composition existing within the various macroalgae classes, which offer the possibility of finding a wide array of primary and secondary metabolites with exciting properties and great potential for pharmacological...
Cosmeceutical Potential of the Green Macroalga Caulerpa Prolifera
Rosa, Gonçalo P.; Seca, Ana M. L.; Barreto, Maria do Carmo; Pinto, Diana C. G. A.The present cosmeceutical industry has been gradually shifting its interest from products based on synthetic compounds to macroalgae-based products due to their interesting antiaging properties but also to their lower cytotoxicity and allergens content. Molecules isolated from macroalgae already showed potential as either active cosmetic ingredients or key elements for the consistency of the cosmetic formulatio...
Overview of phlorotannins’ constituents in Fucales
Catarino, Marcelo D.; Pires, Sónia M. G.; Silva, Sónia; Costa, Filipa; Braga, Susana S.; Pinto, Diana C. G. A.; Silva, Artur M. S.; Cardoso, Susana M.Fucales are an order within the Phaeophyceae that include most of the common littoral seaweeds in temperate and subtropical coastal regions. Many species of this order have long been a part of human culture with applications as food, feedand remedies in folk medicine. Apart from their high nutritional value, these seaweeds are also a well-known reservoir of multiple bioactive compounds with great industrial int...
GC- and UHPLC-MS Profiles as a Tool to Valorize the Red Alga Asparagopsis armata
Pinto, Diana C. G. A.; Lesenfants, Marie L.; Rosa, Gonçalo P.; Barreto, Maria do Carmo; Silva, Artur M. S.; Seca, Ana M. L.Asparagopsis armata Harvey is a red alga native from the southern hemisphere and then introduced in the Mediterranean Sea and the Atlantic Ocean, including the Azores Archipelago, where it is considered an invasive alga. Some studies show that the extracts exhibit antimicrobial and antifouling activities, and it is incorporated in some commercialized cosmetic products. (e.g., Ysaline®). However, knowledge of th...
Bio-Guided Optimization of Cystoseira abies-marina Cosmeceuticals Extraction by...
Rosa, Gonçalo P.; Peixoto, Andreia F.; Barreto, Maria do Carmo; Seca, Ana M. L.; Pinto, Diana C. G. A.Cystoseira abies-marina (reclassified as Gongolaria abies-marina) is a brown seaweed species rich in meroterpenoids, presenting interesting antioxidant, antitumor, and anti-inflammatory activities. However, there is still a lot to uncover regarding the bioactive potential of this species, as evidenced by the lack of records of antiaging activities from Cystoseira abies-marina, making this macroalga an excellent...
Recovery of bacterioruberin and proteins using aqueous solutions of surface-act...
Vaz, Bárbara M. C.; Kholany, Mariam; Pinto, Diana C. G. A.; Macário, Inês P. E.; Veloso, Telma; Caetano, Tânia; Pereira, Joana L.; Coutinho, João A. P.Haloarchaea microorganisms are little explored marine resources that can be a promising source of valuable compounds with unique characteristics, due to their adaptation to extreme environments. In this work, the extraction of bacterioruberin and proteins from Haloferax mediterranei ATCC 33500 was investigated using aqueous solutions of ionic liquids and surfactants, which were further compared with ethanol. De...
Using aqueous solutions of ionic liquids as chlorophyll eluents in solid-phase ...
Vaz, Bárbara M. C.; Martins, Margarida; de Souza Mesquita, Leonardo M.; Neves, Márcia C.; Fernandes, Andreia P. M.; Pinto, Diana C. G. A.There is a need for handy and fast techniques to purify biomolecules, increasing their stability and value, because the separation units are current bottlenecks in downstream processes. Solid-phase extraction is a technique that enables the purification of a compound by its adsorption from a liquid matrix. The AmberLite™ HPR900 OH resin allows the separation of chlorophylls from complex extracts, however the re...
Camel (Camelus spp.) urine bioactivity and metabolome: a systematic review of k...
Iglesias Pastrana, Carlos; Delgado Bermejo, Juan Vicente; Sgobba, Maria Noemi; Navas González, Francisco Javier; Guerra, Lorenzo; Pinto, Diana C. G. A.Up to the present day, studies on the therapeutic properties of camel (Camelus spp.) urine and the detailed characterization of its metabolomic profile are scarce and often unrelated. Information on inter individual variability is noticeably limited, and there is a wide divergence across studies regarding the methods for sample storage, pre-processing, and extract derivatization for metabolomic analysis. Additi...
Plant Flavonoids: Chemical Characteristics and Biological Activity
Dias, Maria Celeste; Pinto, Diana C. G. A.; Silva, Artur M. S.In recent years, more attention has been paid to natural sources of antioxidants. Flavonoids are natural substances synthesized in several parts of plants that exhibit a high antioxidant capacity. They are a large family, presenting several classes based on their basic structure. Flavonoids have the ability to control the accumulation of reactive oxygen species (ROS) via scavenger ROS when they are formed. Ther...