4 documents found, page 1 of 1
Peripartum Hysterectomies over a Fifteen-year Period
Dorigon,Alessandra; Martins-Costa,Sérgio Hofmeister; Ramos,José Geraldo LopesAbstract Objective To determine the indications and outcomes of peripartum hysterectomies performed at Hospital de Clínicas de Porto Alegre (a university hospital in Southern Brazil) during the past 15 years, and to analyze the clinical characteristics of the women submitted to this procedure. Methods A cross-sectional study of 47 peripartum hysterectomies from 2005 to 2019. Results The peripartum hysterectomie...
Insulin stimulation of Akt/PKB phosphorylation in the placenta of preeclampsia ...
Ferreira,Gustavo Dias; Orcy,Rafael Bueno; Martins-Costa,Sérgio Hofmeister; Ramos,José Geraldo Lopes; Brum,Ilma Simoni; Corleta,Helena von EyeCONTEXT AND OBJECTIVE: Preeclampsia is a multi-systemic disease and one of the most frequent severe health problems during pregnancy. Binding of insulin triggers phosphorylation and activates cytoplasmic substrates such as phosphatidylinositol 3 kinase (PI3K). Phosphorylation of membrane phosphoinositide 2 (PIP2) to phosphoinositide 3 (PIP3) by PI3K starts Akt/PKB activation. Defects in phosphorylation of the i...
Risk factors for cardiovascular disease ten years after preeclampsia
Canti,Ivete Cristina Teixeira; Komlós,Márcia; Martins-Costa,Sérgio Hofmeister; Ramos,José Geraldo Lopes; Capp,Edison; Corleta,Helena von EyeCONTEXT AND OBJECTIVE: Preeclampsia is a gestational disease that occurs mainly among nulliparous women after the 20th week of gestation, and frequently close to delivery. The effects of preeclampsia on women's blood pressure over the long term are still controversial. Patients with recurrent preeclampsia or preeclampsia in the early stages of pregnancy appear to present higher risk of hypertension. The aim of ...
Síndrome Hemolítico-Urêmica Pós-parto: Relato de Caso
Ramos,José Geraldo Lopes; Martins-Costa,Sérgio Hofmeister; Barros,Elvino; Schmidt,Adriana Prato; Melo,Márcia Portela deA síndrome hemolítico-urêmica (SHU) é processo microangiopático associado a insuficiência renal, determinando alta morbidade e mortalidade. A gestação pode ser um fator precipitante, por meio de mecanismos ainda não bem estabelecidos. Entram no diagnóstico diferencial a pré-eclâmpsia, a síndrome HELLP, o fígado gorduroso agudo da gestação e a púrpura trombocitopênica trombótica. Relatamos um caso de SHU ocorren...