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A new methodology for polyvalent intravenous immunoglobulin solution production...

Lucena, Antônio Edson de Souza; Sampaio, Divaldo de Almeida; Silva, Ednaldo Rosas da; Paiva, Virgínia Florêncio de; Santiago, Ana Cláudia

Highly purified intravenous immunoglobulin G concentrate (IV IgG) was produced with the use of polyethylene glycol associated to a single-stage precipitation by ethanol, instead of the classic Cohn-Oncley process, which employs cold alcohol as the precipitating agent, in a three-stage process. Precipitation of crude fraction containing more than 95% of immunoglobulin G was performed by liquid chromatography wit...

Date: 2010   |   Origin: Oasisbr
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