Five new withanolides, designated as 15-oxo-nicaphysalin B, 6 β ,7 α -dihydroxynicandrenone 10, 24 α ,25 β -dihydroxy-nicandrenone-2 and a mixture of the epimers 17-(1 α /1 β -methylpropanone)- nicandrenone, in addition to six known others, were isolated from the leaf acetone extract from Nicandra physalodes . The complete structures of the five new withanolides, particularly their relative stereochemistries, w...
A new lactone, 7-epi-griffonilide (1), and six known compounds, 2, 3a - 3c, 4a and 4b, were isolated from the leaves of Bauhinia pentandra (Fabaceae). The structures elucidation of 1 and 2 were based on detailed 2D NMR techniques and spectral comparison with related compounds, leading to complete assignment of the 1H and 13C NMR spectra.
Croton nepetaefolius Baill is the aromatic plant native to northeast of Brazil popularly known as “marmeleiro sabiá”. It is used in folk medicine as a stomachic, a carminative and for the treatment of intestinal colic. A total of 26 compounds were obtained by hydrodistillation and identified by GC - MS and CG - FID in the three essential oils samples , being 5 monoterpenes (36.9%), 7 sesquiterpenes (31.8%) and ...
The essential oil from the leaves of Myrcia ovata Cambess., commonly used in Brazil for the treatment of gastric illnesses, was screened for antimicrobial activity and action in the formation of microbial biofilms by Enterococcus faecalis. The oil was obtained by hydrodistillation using a clevenger-type system. Its chemical composition was analyzed using GC and GC-MS. Both MIC and MBC of the essential oil were ...