Introdução: O Fenómeno de Raynaud (FR) é uma isquemia transitória das extremidades e pode dividir-se em primário e secundário a várias patologias ou fármacos, como os betabloqueadores. A prevalência deste fenómeno pode variar entre 7-14,7%. A patofisiologia é pouco conhecida. A utilização de betabloqueadores com maior afinidade para os adrenorrecetores beta-1, como o bisoprolol, não será protetora do desenvolvi...
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Understanding the complex mechanical behavior of osteochondral tissues in silico is essential for improving experimental models and advancing research in joint health and degeneration. This review provides a comprehensive analysis of the constitutive models currently used to represent the different layers of the osteochondral region, from articular cartilage to subchondral bone, including intermediate regions s...
This paper studies the impact on consumption of the exogenous changes in public wages in Portugal during and after the economic and financial assistance program (2011-2014), by exploiting the variability in the size of such changes across municipalities. The initial wage cuts triggered a marked reduction of private consumption, while the reinstatements in the later years gave rise to an increase, albeit of a sm...
Purpose: Keratoconus is traditionally classified as a noninflammatory corneal ectasia, despite growing evidence suggesting an underlying inflammatory component. This study evaluates whether patients with stable keratoconus exhibit persistent inflammatory activity in tear fluid compared to healthy controls. Methods: Cross-sectional case-control study. Keratoconus progression was evaluated using tomographic and c...
This study aims to assess the influence of root canal preparation, irrigation needle design and its placement depth in the irrigation flow of confluent canals during syringe irrigation. A mandibular molar presenting two confluent canals in its mesial root was sequentially prepared and scanned by micro-computed tomography after mechanical preparation up to ProTaper Next system sizes X2 (25/.06v), X3 (30/.07v) an...
INTRODUCTION: To evaluate the short-term visual and refractive outcomes of V4c-V5 implantable collamer lens implantation, and its safety profile in myopia and myopic astigmatism correction. METHODS: Retrospective unicentric observational study of patients with Implantable collamer lens implantation. Main outcome measures at 6 months were safety, efficacy, predictability, endothelial cell count loss, intraocular...
Ocean acidification (OA) is expected to decrease the strength of bivalves' shells, especially during the early stages of development, with negative consequences to the resilience of natural populations and the economy. The objectives of the present study were to assess the long-term effect of increasing pCO(2) after 217 days of exposure under controlled conditions of pH of similar to 8.2, 8.0, and 7.7 on the st...
Additive manufacturing (AM), also known as three-dimensional (3D) printing, allows the fabrication of complex parts, which are impossible or very expensive to produce using traditional processes. That is the case for dinnerware and artworks (stoneware, porcelain and clay-based products). After the piece is formed, the greenware is fired at high temperatures so that these pieces gain its mechanical strength and ...
A case on rapid prototyping is presented in this work to exemplify the use of learn, make and share activities to promote maritime studies. SMARTBOAT is an initiative from the Escola Superior Náutica Infante D. Henrique, in Portugal, where students are invited to interact with computer-aided design modelling, additive manufacturing and programming. Such initiative is paramount to instigate and promote higher ed...