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High Incidence of Sexually Transmitted Infections in Patients with HIV-Infection

Azevedo, Telma; Brasileiro, Ana; Borges, Fernando; Mansinho, Kamal; Santo, Irene; Azevedo, Jacinta

Introduction: Sexual transmitted infections (STI) are an important health problem and increase the risk for acquisition and transmission of HIV. We aimed to identify STIs diagnosed in patients with known human immunodeficiency virus (HIV) infection and in newly diagnosed ones.Methods: Retrospective analysis of medical charts of individuals attending a specialized STI Clinic from 2009 to 2013.Results: A total of...


A retrospective cross-sectional quantitative molecular approach in biological s...

Pinto, Miguel; Antelo, Minia; Ferreira, Rita; Azevedo, Jacinta; Santo, Irene; Borrego, Maria José; Gomes, João Paulo

Syphilis is the sexually transmitted disease caused by Treponema pallidum, a pathogen highly adapted to the human host. As a multistage disease, syphilis presents distinct clinical manifestations that pose different implications for diagnosis. Nevertheless, the inherent factors leading to diverse disease progressions are still unknown. We aimed to assess the association between treponemal loads and dissimilar d...


Proctitis and Chlamydia trachomatis and Neisseria gonorrhoeae Anorectal Infecti...

Alves, João; Azevedo, Jacinta; Santo, Irene; Borrego, Maria José

Introduction: Sexually transmitted infections (STI) among men who have sex with men (MSM) have increased in recent years, particularly those caused by Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT), both responsible for proctitis and anorectal infections.Methods: Retrospective analysis of the frequency of proctitis and NG and CT anorectal infection in 2420 MSM observed in Outpatient Clinic of STD of ...


Proctite e infeção anoretal por Chlamydia trachomatis e Neisseria gonorrhoeae e...

Alves, João; Azevedo, Jacinta; Santo, Irene; Borrego, Maria José

Introdução: As infeções sexualmente transmissíveis (IST) em homens que têm sexo com homens (HSH) têm aumentado nas últimas décadas, nomeadamente as provocadas por Neisseria gonorrhoeae (NG) e por Chlamydia trachomatis (CT), ambas responsáveis por proctites e infecções anorectais. Material e Métodos: Análise retrospetiva da frequência de proctite e infecção anoretal por NG e CT em 2420 HSH observados na Consulta...


Anogenital Warts in a Major Venereology Clinic: Centro de Saúde da Lapa - Lisbo...

Gameiro, Ana; Alves, João; Santo, Irene; Azevedo, Jacinta

Introduction: Human papillomavirus infection is the most common sexual transmitted infection in the world, being associated with different diseases, namely anogenital warts, recurrent respiratory papillomatosis and anal, cervical, and oropharyngeal cancers. Among sexually active people, approximately 1% has anogenital warts, 90% of cases resulting from genotypes 6 and 11.Material and Methods: Patients diagnosed...

Date: 2016   |   Origin: Acta Médica Portuguesa

Carga treponémica em amostras biológicas correspondentes a diferentes fases clí...

Pinto, Miguel; Antelo, Minia; Ferreira, Rita; Azevedo, Jacinta; Santo, Irene; Borrego, Maria José; Gomes, João Paulo

[PT] Sífilis, a doença sexualmente transmitida causada por Treponema pallidum, apresenta diferentes manifestações clinicas. No entanto, os fatores que levam às diversas progressões da doença permanecem desconhecidos. Este estudo teve como objetivo a quantificação da carga treponémica, em diversas amostras biológicas, para contribuir para uma melhor compreensão da doença. Analisaram-se 309 amostras de DNA de dis...


Diagnóstico laboratorial da infeção por Chlamydia trachomatis, 1991-2014

Dinis, Margarida; Cordeiro, Dora; Santo, Irene; Azevedo, Jacinta; Gomes, João Paulo; Borrego, Maria José

Objetivo: O presente trabalho tem por objetivo apresentar os resultados do diagnóstico laboratorial das infeções por C. trachomatis realizado no Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA) entre 1991 e 2014.


GONOCOCCAL INFECTION IN A SEXUALLY TRANSMITTED INFECTION CLINIC. A RETROSPECTIV...

Barreiros, Hugo; Azevedo, Jacinta; Santo, Irene

Introduction: In the late 70’s gonococcal infection decreased in most Western European Countries. In the 90’s there has been an important increase in the incidence of the disease, mostly in some higher risk groups. Material and methods: This is a retrospective study based in the population attending the STD Clinic of Centro de Saúde da Lapa, between January 2007 and December 2011 (5 years). We assessed epidemio...


GENITAL CHLAMYDIA TRACHOMATIS INFECTION IN A SEXUALLY TRANSMITTED INFECTION CLI...

Travassos, Ana Rita; Borges da Costa, João; Azevedo, Jacinta; Santo, Irene

Introduction: Chlamydia trachomatis genital infection (Ct) is now the most common sexually transmitted bacterial infection (STI) diagnosed in United Kingdom and in United States and its prevalence is highest in persons younger than 25 years. Asymptomatic infection is also common among both men and women.Objectives: To assess epidemiological characteristics and prevalence of Ct in a population of patients attend...


Correlating Chlamydia trachomatis infectious load with urogenital ecological su...

Gomes, João P.; Borrego, Maria J.; Atik, Berna; Santo, Irene; Azevedo, Jacinta; Brito de Sá, Armando; Nogueira, Paulo; Dean, Deborah

The association of infectious burden of Chlamydia trachomatis with patient characteristics and clinical disease may have implications for understanding disease pathogenesis.We examined chlamydial load from 171 urine samples where load was based on copy number of organisms per copy number of eukaryotic cells derived by real-time quantitative PCR. High- (E, F, G) and low-prevalence (Ia, H, J, Ja) genotypes in the...


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