110 documents found, page 1 of 11
Fetal Hemoglobin as a Predictive Biomarker for Retinopathy of Prematurity: A Pr...
Fevereiro-Martins, M; Aguiar, L; Inácio, Â; Cardoso, C; Santos, AC; Marques-Neves, C; Guimarães, H; Pinto, R; Bicho, MBackground/Objectives: Retinopathy of prematurity (ROP) is a leading cause of vision impairment in preterm infants, with its pathogenesis linked to oxygen exposure. Red blood cell (RBC) transfusions, commonly performed in neonatal intensive care units (NICUs), reduce fetal hemoglobin (HbF) fraction, altering oxygen dynamics and potentially contributing to ROP. We aimed to investigate the relationship between RB...
Influence of Functional Variations in Genes of Neurotrophins and Neurotransmitt...
Fevereiro-Martins, M; Santos, AC; Marques-Neves, C; Guimarães, H; Bicho, Mfirst_pagesettingsOrder Article Reprints Open AccessArticle Influence of Functional Variations in Genes of Neurotrophins and Neurotransmitter Systems on the Development of Retinopathy of Prematurity by Mariza Fevereiro-Martins 1,2,3,4,*,Ana Carolina Santos 1,2ORCID,Carlos Marques-Neves 1,2,5,Hercília Guimarães 6ORCID,Manuel Bicho 1,2,3ORCID andon behalf of the GenE-ROP Study Group † 1 Faculdade de Medicina, Uni...
Retinopathy of Prematurity in Eight Portuguese Neonatal Intensive Care Units: I...
Fevereiro-Martins, M; Santos, AC; Marques-Neves, C; Bicho, M; Guimarães, HBackground/Objectives: Retinopathy of prematurity (ROP) is a retinal neovascular disease affecting preterm infants. Identifying risk factors for its development and progression is critical for effective screening and prevention. This study aimed to analyze the incidence of ROP and identify key risk factors for its development and progression. Methods: We conducted a prospective, observational cohort study on 45...
Physical activity, sedentary behaviour, and childhood asthma: a European collab...
Eijkemans, M; Mommers, M; Harskamp-van Ginkel, MW; Vrijkotte, TGM; Ludvigsson, J; Faresjö, Å; Bergström, A; Ekström, S; Grote, V; Koletzko, BOBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. SETTING: Ch...
Obstructive sleep related breathing disorders and cardiometabolic risk factors ...
Costa, M; Correia-Costa, L; Santos, AC; Azevedo, I"Background Pediatric obstructive sleep related breathing disorders (SRBD) are an important under-diagnosed health problem with associated cardiometabolic comorbidities, demonstrated with polysomnographic studies in selected samples. Our main goal was to assess the prevalence of SRBD in a population-based cohort and to analyze its association with cardiometabolic risk factors, in general and by sex. Methods Ped...
Complete blood count parameters as biomarkers of retinopathy of prematurity: a ...
Fevereiro-Martins, M; Santos, AC; Marques-Neves, C; Guimarães, H; Bicho, M; Afonso, C; Ferreira, J; Espírito Santo, R; Teixeira, F; Rosa, RPurpose: To evaluate complete blood count (CBC) parameters in the first week of life as predictive biomarkers for the development of retinopathy of prematurity (ROP). Methods: Multicenter, prospective, observational study of a cohort of preterm infants born with gestational age (GA) < 32 weeks or birth weight < 1500 g in eight Portuguese neonatal intensive care units. All demographic, clinical, and laboratory d...
Genetic Modulation of the Erythrocyte Phenotype Associated with Retinopathy of ...
Fevereiro-Martins, M; Santos, AC; Marques-Neves, C; Guimarães, H; Bicho, MThe development of retinopathy of prematurity (ROP) may be influenced by anemia or a low fetal/adult hemoglobin ratio. We aimed to analyze the association between DNA methyltransferase 3 β (DNMT3B) (rs2424913), methylenetetrahydrofolate reductase (MTHFR) (rs1801133), and lysine-specific histone demethylase 1A (KDM1A) (rs7548692) polymorphisms, erythrocyte parameters during the first week of life, and ROP. In to...
Using Digital Tools to Study the Health of Adults Born Preterm at a Large Scale...
Lorthe, E; Santos, C; Ornelas, JP; Doetsch, JN; Marques, SCS; Teixeira, R; Santos, AC; Rodrigues, C; Gonçalves, G; Sousa, PF; Lopes, JC; Rocha, ABackground: Preterm birth is a global health concern. Its adverse consequences may persist throughout the life course, exerting a potentially heavy burden on families, health systems, and societies. In high-income countries, the first children who benefited from improved care are now adults entering middle age. However, there is a clear gap in the knowledge regarding the long-term outcomes of individuals born p...
Changes in screen time from 4 to 7 years of age, dietary patterns and obesity: ...
Figueira, M; Santos, AC; Gregório, Maria João; Araújo, JBackground and aims: Increased screen exposure is associated with unhealthy eating behaviours and obesity. Screen time (ST) changes from pre-school to school age, and associations with dietary patterns (DP) and obesity remain unknown. We, therefore, analysed ST changes from 4 to 7 years of age, associated factors, and the relation with DP and obesity.Methods and results: We included 4531 children evaluated at 4...
Association between children's food insecurity and a Healthy Eating Index in Po...
Maia, I; Oliveira, A; Severo, M; Santos, ACEvidence on the association between children's food insecurity (FI) and dietary patterns (DPs) is scarce. This study assessed the association between children's FI and a priori and a posteriori-defined DPs in a Portuguese population-based sample of children. A cross-sectional study including 2800 children from the ten-year-old follow-up of the Generation XXI birth cohort was performed. Data on food security sta...