3 documents found, page 1 of 1
Metabolic Phenotypes in Asthmatic Adults: Relationship with Inflammatory and Cl...
Santos, Adalberto; Pité, Helena; Loureiro, Cláudia Chaves; Rocha, Sílvia M.; Taborda-Barata, LuísBronchial asthma is a chronic disease that affects individuals of all ages. It has a high prevalence and is associated with high morbidity and considerable levels of mortality. However, asthma is not a single disease, and multiple subtypes or phenotypes (clinical, inflammatory or combinations thereof) can be detected, namely in aggregated clusters. Most studies have characterised asthma phenotypes and clusters ...
Changes in Glycolytic Pathway in SARS-COV 2 Infection and Their Importance in U...
Santos, Adalberto; Póvoa, Pedro; Paixão, Paulo; Mendonça, António; Barata, Luís Manuel TabordaCOVID-19 is an infectious disease caused by Coronavirus 2 (SARS-CoV-2) that may lead to a severe acute respiratory syndrome. Such syndrome is thought to be related, at least in part, to a dysregulation of the immune system which involves three main components: hyperactivity of the innate immune system; decreased production of type 1 Interferons (IFN) by SARS-CoV-2-infected cells, namely respiratory epithelial c...
Criação de uma equipa programática de investigação, desenvolvimento e inovação ...
Santos, AdalbertoEm tempos de abundante disponibilidade de informação e de imperiosa necessidade de judiciosa gestão dos recursos, as ferramentas de planeamento, gestão e controlo dos investimentos em capacidades militares devem ser instrumentos presentes e transversalmente explorados, contribuindo para a desejada eficácia e prontidão operacional. A visão holística das capacidades no contexto dos seus ciclos de vida deve também...