13 documents found, page 1 of 2
Influence of functional variations in genes of neurotrophins and neurotransmitt...
Fevereiro-Martins, Mariza; Santos, Ana Carolina; Marques-Neves, Carlos; Guimarães, Hercília; Bicho, ManuelRetinal neurodevelopment, vascularization, homeostasis, and stress response are influenced by factors such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), tyrosine hydroxylase (TH), and erythropoietin (EPO). As retinopathy of prematurity (ROP) is a neurovascular retinal disease, this study analyzed the contributions of NGF (rs6330), BDNF (rs7934165), TH (rs10770141), and EPO (rs507392) g...
A relação entre a ansiedade e as funções cognitivas em sujeitos toxicodependentes
Santos, Ana CarolinaO consumo de substâncias psicoativas pode levar ao desenvolvimento de alguns tipos de psicopatologia, nomeadamente a ansiedade e, por isso, alterações nas funções cognitivas. Com efeito um dos órgãos mais afetados pelo consumo de substâncias psicoativas é o cérebro, particularmente nos neurotransmissores e recetores com consequências no funcionamento cognitivo e no comportamento quotidiano do indivíduo. O objet...
The interplay between HPV, other sexually transmissible infections and genital ...
Gonçalves-Nobre, J. Guilherme; Matos, Andreia; Carreira, Mariana; Santos, Ana Carolina; Veiga, Luisa; Ginete, Catarina; Brito, Miguel; Pires, MarinaBackground: The importance of Cervicovaginal Microbiota in protecting against infections (such as HPV) is already well established, namely through Lactobacillus spp., as well as the mechanism through which HPV leads to Cervical Neoplasia. However, it is not possible to classify HPV as a complete carcinogen. Thus, the importance of exploring Cervicovaginal dysbiosis to decipher this interaction with HPV takes on...
The interplay between HPV, other sexually transmissible infections and genital ...
Gonçalves Nobre, José Guilherme; Matos, Andreia; Carreira, Mariana; Santos, Ana Carolina; Veiga, Luisa Carvalho; Ginete, Catarina; Brito, MiguelBackground: The importance of Cervicovaginal Microbiota in protecting against infections (such as HPV) is already well established, namely through Lactobacillus spp., as well as the mechanism through which HPV leads to Cervical Neoplasia. However, it is not possible to classify HPV as a complete carcinogen. Thus, the importance of exploring Cervicovaginal dysbiosis with the intention of deciphering this interac...
Influence of the TAS2R38 gene single nucleotide polymorphisms in metabolism and...
Mendes Costa, Marta; Silva, Alda Pereira da; Santos, Ana Carolina; Ferreira, Joana; Mascarenhas, Mário Rui; Bicho, Manuel; Barbosa, AnaThe gene TAS2R38 single nucleotide polymorphisms (SNPs-P49A, A262V and V296I) can condition bitter tasting by PAV (proline–alanine–valine) and non-bitter-tasting by AVI (alanine–valine–isoleucine) homozygosity. We evaluated this polymorphisms association with thyroid function, metabolism and anthropometry parameters determined by: Endpoint analysis (SNPs); DXA (fat mass-%, total fat mass—kg, lean mass—kg); Stan...
Genetic modulation of the erythrocyte phenotype associated with retinopathy of ...
Fevereiro-Martins, Mariza; Santos, Ana Carolina; Marques-Neves, Carlos; Guimarães, Hercília; Bicho, ManuelThe development of retinopathy of prematurity (ROP) may be influenced by anemia or a low fetal/adult hemoglobin ratio. We aimed to analyze the association between DNA methyltransferase 3 β (DNMT3B) (rs2424913), methylenetetrahydrofolate reductase (MTHFR) (rs1801133), and lysine-specific histone demethylase 1A (KDM1A) (rs7548692) polymorphisms, erythrocyte parameters during the first week of life, and ROP. In to...
Complete blood count parameters as biomarkers of retinopathy of prematurity: a ...
Fevereiro-Martins, Mariza; Santos, Ana Carolina; Marques-Neves, Carlos; Guimarães, Hercília; Bicho, Manuel; Afonso, Conceição; Ferreira, JoanaPurpose: To evaluate complete blood count (CBC) parameters in the first week of life as predictive biomarkers for the development of retinopathy of prematurity (ROP). Methods: Multicenter, prospective, observational study of a cohort of preterm infants born with gestational age (GA) < 32 weeks or birth weight < 1500 g in eight Portuguese neonatal intensive care units. All demographic, clinical, and laboratory d...
Estudo do perfil dos Gestores Hoteleiros
Santos, Ana CarolinaPortugal foi considerado o Melhor Destino Europeu pelos World Travel Awards, entre 2017-2020, e arrecadou cerca de 21 óscares do turismo. Pela importância que o turismo assume, conhecer o perfil da liderança da hotelaria em Portugal, identificar os atributos característicos destes e perceber como colaborar no exercício desta profissão tem cada vez mais importância. Caracterizar o perfil do gestor hoteleiro em P...
Preservando a memória: Centro de Interpretação do Patrimônio Cultural na cidade...
Santos, Ana CarolinaLaguna é uma cidade com forte potencial atrativo turístico cultural, devido aos inúmeros patrimônios culturais materiais e imateriais presentes no município. Diante disso, com a finalidade de preservar esses bens e a memória e identidade que eles carregam, o presente Trabalho de Conclusão de Curso consiste na elaboração do anteprojeto de um Centro de Interpretação do Patrimônio Cultural na cidade de Laguna, SC,...
Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hyper...
da Silva, Inês Vieira; Santos, Ana Carolina; Matos, Andreia; Silva, Alda Pereira da; Soveral, Graça; Rebelo, Irene; Bicho, ManuelPreeclampsia (PE), a pregnancy disorder influenced by oxidative stress and hypoxia, affects the health of the mother and baby and is associated with an increased risk of future hypertension (HT). Aquaporins are a family of water channels, comprising members that also transport glycerol (aquaglyceroporins) and hydrogen peroxide (peroxiporins), key molecules for metabolic homeostasis and redox signaling. Here, we...