34 documents found, page 1 of 4
Genomic diversity and resistance profile of Mycobacterium avium clinical strain...
Rodrigues, Joana; Rodrigues, Irene; Carneiro, Sofia; Silva, Sónia; Santos, Andrea; Macedo, RitaIntroduction: In recent years, opportunistic infections with nontuberculous mycobacteria (NTM) have gained increasing importance in public health, with Mycobacterium avium being the most responsible species for the increase of human disease cases. These infections manifest mainly at the respiratory level, and disseminated infection may also occur, especially in immunocompromised individuals. Currently, the mode...
Epidemiological Data and Antimicrobial Resistance of Campylobacter spp. in Port...
Duarte, Andreia; Pereira, Luísa; Lemos, Maria-Leonor; Pinto, Miguel; Rodrigues, João Carlos; Matias, Rui; Santos, Andrea; PTCampyNet; Oleastro, MónicaThis study extensively analyzed campylobacteriosis surveillance in Portugal from 2009 to 2021, aiming to investigate demographic shifts, seasonal variations, and antimicrobial resistance (AMR) within Campylobacter isolates. Surveillance network and sentinel laboratory-based system data revealed a substantial under-notification of campylobacteriosis cases, suggesting an underestimated disease burden. Notificatio...
EANM procedural recommendations for managing the paediatric patient in diagnost...
Camoni, Luca; Santos, Andrea; Luporsi, Marie; Grilo, Ana; Pietrzak, Agata; Gear, Jonathan; Zucchetta, Pietro; Bar-Sever, ZviPurpose: The manuscript aims to characterize the principles of best practice in performing nuclear medicine procedures in paediatric patients. The paper describes all necessary technical skills that should be developed by healthcare professionals to ensure the best possible care for paediatric patients, as it is particularly challenging due to the psychological and physical conditions of children. Methods: We p...
Genome-Scale Characterization of Mycobacterium abscessus Complex Isolates from ...
Carneiro, Sofia; Pinto, Miguel; Silva, Sónia; Santos, Andrea; Rodrigues, Irene; Santos, Daniela; Duarte, Sílvia; Vieira, Luís; Gomes, João PauloThe Mycobacterium abscessus complex (MABC) is an emerging, difficult to treat, multidrug-resistant nontuberculous mycobacteria responsible for a wide spectrum of infections and associated with an increasing number of cases worldwide. Dominant circulating clones (DCCs) of MABC have been genetically identified as groups of strains associated with higher prevalence, higher levels of antimicrobial resistance, and w...
Microevolution of a Mycobacteroides abscessus subsp. bolletii strain in a clini...
Santos, Andrea; Pinto, Miguel; Carneiro, Sofia; Silva, Sónia; Rodrigues, Irene; Munhá, João; Gomes, João Paulo; Macedo, RitaMycobacteroides abscessus complex (MAB), a fast-growing nontuberculous mycobacterium, is emerging as a significant infectious disease threat, due to both intrinsic and acquired resistance mechanisms to antibiotics and disinfectants and the need for extensive and multidrug regimens for treatment. Despite the prolonged regimens, outcomes are poor and persistence cases have been reported. Here, we describe clinica...
Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective...
Nazareth, Cláudia; Leitão, Inês; Reis, Ernestina; Inácio, Hugo; Martins, Filomena; Ramalheira, Elmano; Cunha, Flávia; Santos, Carla; Lino, SaraIntroduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among hospitalized patients in Portugal.Material and Methods: Retrospective study conducted in six public hospital centers in Portugal. All primary Clostridioides difficile infe...
Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective...
Nazareth, Cláudia; Leitão, Inês; Reis, Ernestina; Inácio, Hugo; Martins, Filomena; Ramalheira, Elmano; Cunha, Flávia; Santos, Carla; Lino, SaraIntroduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among hospitalized patients in Portugal. Material and methods: Retrospective study conducted in six public hospital centers in Portugal. All primary Clostridioides difficile inf...
Cancer patient experience in a nuclear medicine department: comparison between ...
Grilo, Ana Monteiro; Vieira, Lina Oliveira; Carolino, Elisabete; Costa, Melissa; Galaio, Salomé; Melo, Inês; Geão, Ana; Santos, Andrea; Colarinha, PaulaObjective: To assess the emotional impact on cancer patients undergoing Nuclear Medicine scans and identify how professionals can improve patient experience. Methods: 94 patients undergoing a Bone Scan (BS) or a Positron emission tomography/Computed Tomography (18F-FDG PET/CT) completed two Scan Experience Questionnaires and the State Anxiety Inventory (STAI-S) prior to the scan and after image acquisition. Res...
Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to ...
Marques, Andreia T.; Vítor, Jorge M.B.; Santos, Andrea; Oleastro, Mónica; Vale, Filipa F.For a long time Helicobacter pylori infections have been treated using the macrolide antibiotic, clarithromycin. Clarithromycin resistance is increasing worldwide and is the most common cause of H. pylori treatment failure. Here we review the mechanisms of antibiotic resistance to clarithromycin, detailing the individual and combinations of point mutations found in the 23S rRNA gene associated with resistance. ...
Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to ...
Marques, Andreia T.; Vítor, Jorge M. B.; Santos, Andrea; Oleastro, Mónica; Vale, FilipaFor a long time Helicobacter pylori infections have been treated using the macrolide antibiotic, clarithromycin. Clarithromycin resistance is increasing worldwide and is the most common cause of H. pylori treatment failure. Here we review the mechanisms of antibiotic resistance to clarithromycin, detailing the individual and combinations of point mutations found in the 23S rRNA gene associated with resistance. ...