7 documents found, page 1 of 1
Citizen Science to Raise Antimicrobial Resistance Awareness in the Community: T...
Gil-Serna, J; Antunes, Patrícia; Campoy, S; Cid, A; Cobo-Molinos, A; Durao, P; Fajardo, C; Fouz, B; Freitas, AR; Grosso, F; de Groot, PWJ; de Miguel, TAntimicrobial resistance (AMR) poses a global threat to human, animal and environmental health. Among the multidisciplinary tasks aimed at collectively tackling the AMR crisis, surveillance, research and education stand as major priorities. Based on a crowdsourcing research strategy, the MicroMundo project, a partner of the Tiny Earth initiative in Spain and Portugal, has been developed and consolidated with su...
Efficacy and safety of pharmacological interventions for managing sickle cell d...
Tonin, FS; Ginete, C; Ferreira, J; Delgadinho, M; Santos, B; Fernandez-Llimos, F; Brito, MThis study aimed to synthesize the evidence on the effects of disease-modifying agents for managing sickle cell disease (SCD) in children and adolescents by means of a systematic review with network meta-analyses, surface under the cumulative ranking curve (SUCRA) and stochastic multicriteria acceptability analyses (SMAA) (CRD42022328471). Eightteen randomized controlled trials (hydroxyurea [n = 7], l-arginine ...
Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systemat...
Gaspar, LS; Santos-Carvalho, A; Santos, B; Carvalhas-Almeida, C; Barros-Viegas, AT; Oliveiros, B; Donato, H; Santos, C; Moita, J; Cavadas, C; Álvaro, ARBackground: Obstructive Sleep Apnea (OSA) has been recognized as a major health concern worldwide, given its increasing prevalence, difficulties in diagnosis and treatment, and impact on health, economy, and society. Clinical guidelines highlight the need of biomarkers to guide OSA clinical decision-making, but so far, without success. In this systematic review and meta-analysis, registered on the International...
Importância da citologia na deteção de lesões do endométrio
Santos, B; Oliveira, C; Gomes, N; Ramos, S; Oliveira, D; Silva, AS; Adriano, A; Luís, A; Mendonça, PO presente estudo reporta a citologia de uma mulher de 66 anos, que apresenta um epitélio atrófico com fundo inflamatório. Identificaram-se agregados tridimensionais de células glandulares com sobreposição celular, anisocariose, aumento nuclear, hipercromasia moderada, presença de nucléolos e cromatina grosseira, irregularmente distribuída. O diagnóstico citológico foi de células glandulares atípicas sem outra ...
Retina and Choroid of Diabetic Patients Without Observed Retinal Vascular Chang...
Ferreira, J; Proença, R; Alves, M; Dias-Santos, A; Santos, B; Cunha, JP; Papoila, AL; Abegão Pinto, LPURPOSE: To identify changes in choroidal thickness (CT) and all retinal layers of diabetic patients without diabetic retinopathy (DR) after 1 year of follow-up. DESIGN: Prospective observational cohort study. METHODS: Overall, 125 diabetic patients without DR were included. Two visits were scheduled: the first visit (V1) and a second visit after 12 months (V2). At both visits, patients received a complete opht...
Retinal Neurodegeneration in Diabetic Patients Without Diabetic Retinopathy
Tavares Ferreira, J; Alves, M; Dias-Santos, A; Costa, L; Santos, B; Cunha, JP; Papoila, AL; Abegão Pinto, LPURPOSE: To compare the thickness of all retinal layers between a nondiabetic group and diabetic patients without diabetic retinopathy (DR). METHODS: Cross-sectional study, in which all subjects underwent an ophthalmic examination including optical coherence tomography. After automatic retinal segmentation, each retinal layer thickness (eight separate layers and overall thickness) was calculated in all nine Ear...
Is there still a place for involutional melancholia nowadays?
Simões, S; Mesquita, J; Santos, B; Silva, L