154 documents found, page 1 of 16
Knowledge and Consequences of Violence Against Health Professionals in Southern...
Zangão, M; Gemito, L; Serra, I; Cruz, D; Barros, M; Chora, M; Santos, C; Coelho, A; Alves, ElisabeteBackground: Violence against health professionals is a global and growing problem, with significant impacts on the quality of care and the mental health of workers. Objectives: To analyze the level of knowledge, reporting practices and consequences of violence against health professionals in the Alentejo region (southern Portugal). Methods: This was an observational, cross-sectional study involving 440 health p...
Home Ultrasound: A Contemporary and Valuable Tool for Palliative Medicine
Monteiro, AC; França de Santana, T; Morais, M; Santos, C; Aurélio, J; Santos, I; Cruz, S; Vázquez, D; Ferreira Arroja, S; Mariz, JThis narrative review explores the application of point-of-care ultrasound (POCUS) in palliative care and its feasibility in home care settings. POCUS has the potential to streamline diagnostic strategies without patient transfer to the hospital, expedite timely symptomatic relief, and reduce complications from specific palliative interventions. The advent of handheld ultrasound devices has made it an attractiv...
Pharmacological NF-κB inhibition decreases cisplatin chemoresistance in muscle-...
Gil da Costa, Rui; Levesque, C; Bianchi-Frias D; Chatterjee, P; Lam, HM; Santos, C; Coleman, IM; Ferreirinha, P; Vilanova, M; Pinto da Cunha, NMost patients with muscle-invasive bladder cancer (MIBC) are not cured with platinum chemotherapy. Up-regulation of nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) is a major mechanism underlying chemoresistance, suggesting that its pharmacological inhibition may increase platinum efficacy. NF-κB signaling was investigated in two patient cohorts. The Cancer Genome Atlas (TCGA) was used to...
Pulmonary and Gastrointestinal Parasitic Infections in Small Ruminant Autochtho...
Pereira, MA; Vila-Viçosa, MJ; Coelho, C; Santos, C; Esteves, F; Cruz, R; Gomes, L; Henriques, D; Vala, H; Nóbrega, C; Mega, AC; Melo, C; Malva, MThe production of small ruminant autochthonous breeds in the Centre region of Portugal is practiced in a semi-extensive husbandry system, exposing animals to parasitic infections. The main objective of this study was to estimate the prevalence of lungworm infection and identify risk factors. Fecal samples of 203 goats and 208 sheep from 30 herds were collected per rectum and subjected to the modified Baermann t...
Feasibility and Acceptability of Pediatric Smartphone Lung Auscultation by Pare...
Santos-Silva, C; Ferreira-Cardoso, H; Silva, S; Vieira-Marques, P; Valente, JC; Almeida, R; Fonseca, JA; Santos, C; Azevedo, I; Jácome, CBackground: The use of a smartphone built-in microphone for auscultation is a feasible alternative to the use of a stethoscope, when applied by physicians. Objective: This cross-sectional study aims to assess the feasibility of this technology when used by parents—the real intended end users. Methods: Physicians recruited 46 children (male: n=33, 72%; age: mean 11.3, SD 3.1 y; children with asthma: n=24, 52%) d...
Molecular evidence of sporadic Coxiella burnetii excretion in sheep milk, centr...
Pires, H; Santos-Silva, S; Cruz, AVS; Cardoso, L; Lopes, AP; Pereira, MA; Nóbrega, C; Mega, AC; Santos, C; Cruz, R; Esteves, F; Vala, H; Matos, ACCoxiella burnetii is the etiologic agent of Q fever, a worldwide zoonosis. Cattle, sheep and goats are considered the main reservoirs of the disease. Transmission to humans occurs mainly through the inhalation of infectious aerosols from milk, faeces, urine, and birth products from infected ruminants. In this study, a 2-year longitudinal approach was performed to ascertain the excretion of C. burnetii in bulk t...
Expert Perspectives on the Management of Alpha 1-Antitrypsin Deficiency
Conde, B; Costa, F; Gomes, J; Lopes, AP; Mineiro, A; Rodrigues, O; Santos, C; Semedo, L; Sucena, M; Guimarães, CAlpha 1-antitrypsin deficiency is an inherited autosomal codominant disorder, which predisposes patients to lung and/or liver disease. Even though it is considered rare, it is one of the most frequent genetic disorders worldwide, albeit remaining underdiagnosed. Several organizations and societies, including the Portuguese Society of Pulmonology have been elaborating guidelines and recommendations for the diagn...
Intervenção do Enfermeiro de Reabilitação na Capacitação da Pessoa com Insufici...
Varão, S; Mata, R; Aleixo, L; Silva, V; Santos, C; Silva, CA Insuficiência Cardíaca (IC) afeta 26 milhões de pessoas, com custos elevados devido à redução da qualidade de vida, aumento do sofrimento e mortalidade. A evidência científica realça que programas de capacitação e reabilitação cardiovascular diminuem hospitalizações (Fonseca 2018). Capacitar a pessoa para a gestão da IC (Geral), aumentar a literacia em saúde, implementar um plano educacional e de reabilitação...
Measuring Adherence to Inhaled Control Medication in Patients with Asthma: Comp...
Cachim, A; Pereira, AM; Almeida, R; Amaral, R; Alves‐Correia, M; Vieira‐Marques, P; Chaves‐Loureiro, C; Ribeiro, C; Cardia, F; Gomes, J; Vidal, CBackground: Previous studies have demonstrated the feasibility of using an asthma app to support medication management and adherence but failed to compare with other measures currently used in clinical practice. However, in a clinical setting, any additional adherence measurement must be evaluated in the context of both the patient and physician perspectives so that it can also help improve the process of share...
Levosimendan in Outpatients with Advanced Heart Failure: Single-Center Experien...
Ferreira Reis, J; Gonçalves, A; Ilhão Moreira, R; Pereira-da-Silva, T; Timóteo, AT; Pombo, D; Carvalho, T; Correia, C; Santos, C; Cruz Ferreira, RIntroduction: Patients with advanced heart failure (HF) have high morbidity and mortality, with only a small proportion being eligible for advanced therapies. Intermittent outpatient levosimendan infusion has been shown to provide symptomatic relief and reduce the rate of HF events. Our aim was to assess the safety and efficacy of outpatient levosimendan administration in an advanced HF population. Methods: Thi...