2 documents found, page 1 of 1
A complex scenario of tuberculosis transmission is revealed through genetic and...
Rito, T; Matos, C; Carvalho, C; Machado, H; Rodrigues, G; Oliveira, O; Ferreira, E; Gonçalves, J; Maio, L; Morais, C; Ramos, H; Guimarães, JTBackground: Tuberculosis (TB) incidence is decreasing worldwide and eradication is becoming plausible. In low-incidence countries, intervention on migrant populations is considered one of the most important strategies for elimination. However, such measures are inappropriate in European areas where TB is largely endemic, such as Porto in Portugal. We aim to understand transmission chains in Porto through a gene...
To Be or Not to Be a Pseudogene: A Molecular Epidemiological Approach to the mc...
Santos, CL; Nebenzahl-Guimaraes, H; Mendes, MV; Soolingen, D; Correia-Neves, MTuberculosis presents a myriad of symptoms, progression routes and propagation patterns not yet fully understood. Whereas for a long time research has focused solely on the patient immunity and overall susceptibility, it is nowadays widely accepted that the genetic diversity of its causative agent, Mycobacterium tuberculosis, plays a key role in this dynamic. This study focuses on a particular family of genes, ...