2 documents found, page 1 of 1
Purification and characterization of a lectin from seeds of Vatairea macrocarpa...
Cavada, Benildo S.; Santos, Cláudia F.; Grangeiro, Thalles B.; Nunes, Edson P.; Sales, Patricia V. P.; Ramos, Ronaldo L.; Sousa, Flávia A. M. deThe protein, a galactose binding lectin made up of a misture of full length chains and endogenous C- and N-terminal fragments, was purified from Vatairea macrocarpa seeds and its properties were studied. A lectin from Vatairea macrocarpa Duke seeds (VML) was isolated using affinity chromatography on a guar gum column. The lectin, a glycoprotein without erythrocyte specificity, displays specificity to galactose ...
Potent nonopioid antinociceptive activity of telocinobufagin in models of acute...
Feitosa, Geissy I.M.C.; Carvalho, Isabella F.; Coelho, Edivaldo B.S.; Monteiro, Marla R.B; Medeiros, Rafael L.; Carvalho, Ellaine D.F.Introduction: In recent decades, several researches have been conducted in search of new analgesics that do not present the side effects of opioids. In this context, animal venoms contain natural painkillers that have been used for the development of new analgesics. Objective: The aims of this study were to evaluate the antinociceptive effects of telocinobufagin (TCB), a bufadienolide isolated from Rhinella jim...