75 documents found, page 1 of 8
Oncology care humanization in adults: a scoping review protocol
Lopes, Ana Sofia; Ribeiro, Ana Lúcia; Lamas, Bárbara; Santos, Daniela; Fernandes, Davide; Silva, Rosa; Marques, PauloObjective: The goal of this review is to identify and map health professionals’ attitudes and behaviors that promote humanization of the care provided to adults with cancer, regardless of disease stage or treatment nature, in all health care provision contexts. Introduction: In the challenging context of oncology care, it becomes imperative to adopt a humanized care paradigm. This paradigm should foster a relat...
Novel benzothiazole Boc-Phe-Phe-Bz derivative dipeptide forming fluorescent and...
Baptista, Rosa Maria Ferreira; Santos, Daniela; Cunha, N. F.; Castro, Maria Cidália Rodrigues; Rodrigues, Pedro António Veiga; Machado, A. V.This work explores the self-assembly and optical properties of a novel chiral, aromatic-rich Boc-Phe-Phe dipeptide derivative functionalized with a benzothiazole bicyclic ring that forms supramolecular structures. Leveraging the well-known self-assembling capabilities of diphenylalanine dipeptides, this modified derivative introduces a heterocyclic benzothiazole unit that significantly enhances the fluorescence...
The Composting of Water Hyacinth: A Life Cycle Assessment Perspective
Serafini, Lais Fabiana; Arrobas, Margarida; Rodrigues, Manuel Ângelo; Feliciano, Manuel; Miguens, Filomena; Oliveira, Verónica; Santos, DanielaWater hyacinth is an invasive species that causes eutrophication in lentic waters. While mechanical removal is effective, it generates hazardous waste with biological contamination risk. Composting is a safe waste treatment option, inhibiting seeds and yielding agriculturally suitable compost. Life cycle assessment evaluated the environmental impacts of six composting piles using eight different by-products (po...
Mutational Analysis of Colistin-Resistant Pseudomonas aeruginosa Isolates: From...
De Sousa, Telma; Wang, Hsin-Yao; Lin, Ting-Wei; Caniça, Manuela; Ramos, Miguel J.N.; Santos, Daniela; Silva, Catarina; Saraiva, Sónia; Beyrouthy, RachaThis study analyzed eleven isolates of colistin-resistant Pseudomonas aeruginosa, originating from Portugal and Taiwan, which are associated with various pathologies. The results revealed significant genetic diversity among the isolates, with each exhibiting a distinct genetic profile. A prevalence of sequence type ST235 was observed, characterizing it as a high-risk clone, and serotyping indicated a predominan...
Pseudomonas aeruginosa: One Health approach to deciphering hidden relationships...
de Sousa, Telma; Machado, Sandro; Caniça, Manuela; Ramos, Miguel J.N.; Santos, Daniela; Ribeiro, Miguel; Hébraud, Michel; Igrejas, GilbertoAims: Antimicrobial resistance in Pseudomonas aeruginosa represents a major global challenge in public and veterinary health, particularly from a One Health perspective. This study aimed to investigate antimicrobial resistance, the presence of virulence genes, and the genetic diversity of P. aeruginosa isolates from diverse sources. Methods and results: The study utilized antimicrobial susceptibility testing, g...
BlaGES-6 producing Pseudomonas aeruginosa ST235 is involved in resistance to di...
de Sousa, Telma; Machado, Sandro; Carvalho, Márcia; Caniça, Manuela; Ramos, Miguel J.N.; Santos, Daniela; Beyrouthy, Racha; Bonnet, RichardMultidrug resistance in Pseudomonas aeruginosa, particularly resistance to carbapenem, represents a major challenge for public health. This study investigated resistance mechanisms in three P. aeruginosa isolates: HU63 (blaGES-6 carbapenemase-positive), HU141 (carbapenem-resistant without carbapenemase), and PAO1 (control). Genomic analysis revealed distinct sequence types (ST235 for HU63, ST253 for HU141) and ...
Phos4Cycle – Monitorização de fosfatos das atividades agropecuárias para a util...
Oliveira, Verónica; Miguens, Maria Filomena; Santos, Daniela; Galhano, Cristina; Pato, Rosinda; Fajardo, Ana Sofia; Ferreira, Carla; Martin, JulioA poluição do solo e da água por fosfatos, decorrente da agricultura e pecuária, representa um desafio crescente no espaço SUDOE (Portugal, Espanha e França). A elevada dependência da agricultura intensiva em fertilizantes solúveis e pouca reposição da matéria orgânica, têm resultado na degradação da qualidade dos solos e concentrações elevadas de nutrientes nas águas superficiais. O projeto Phos4Cycle visa pro...
Caracterização microbiológica de solo tratado com compostos orgânicos de jacint...
Silva, Célia; Dias, Susana; Oliveira, Verónica; Rodrigues, Edite; Miguens, Maria Filomena; Santos, DanielaOs compostos orgânicos agrícolas são corretivos do solo resultantes da transformação microbiológica da matéria orgânica fresca, aumentando a fração estável da mesma e a reserva de nutrientes disponibilizados através da mineralização do composto, sendo esperado o aumento da biodiversidade microbiana e respetiva funcionalidade dos solos. O jacinto-de-água (Eichhornia crassipes) é uma planta invasora aquática que ...
Risk of colonization with multidrug-resistant gram-negative bacteria among trav...
Pedro, Diogo; Santos, Daniela; Meneses, Maria; Gonçalves, Fátima; Jantarada Domingos, Gonçalo; Caneiras, CatiaGlobalization in the 21st century has posed several challenges. In particular, the spread of multidrug-resistant bacterial strains, especially Gram-negative bacteria, which are prevalent in certain regions of the world, is one of the most critical issues. This raises concerns about the risks associated with the booming tourism industry and migratory flows. In fact, even transient colonization with multidrug-res...
Development of biomimetic human nails using electrospun keratin nanofibers and ...
Fernandes, Diana; Silva, Francisca; Santos, Daniela; Fernandes, Eduarda; Amaral, Maria; Baptista, Rosa; Ribeiro, Artur; Lopes, Carla; Lúcio, MarleneIntroduction: Nail infections, particularly onychomycosis, affect approximately 5.5% of the global population, significantly impacting quality of life. Beyond aesthetic concerns, these conditions cause discomfort, functional impairment, and psychological distress. A major challenge in treatment is the low transungual permeability of the nail plate, restricting drug penetration and reducing therapeutic efficacy....