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Editorial: From learning to publishing: a commitment to research integrity
Santos, FátimaAs Athena Health & Research Journal approaches its second anniversary, this milestone provides an important opportunity for us as an institution to reaffirm our commitment to rigorous, ethical and credible research in the health sciences. The journal’s continued development shows our shared academic responsibility to promote scientific excellence and integrity, as well as engagement with evolving research p...
Establishment of a Protocol for the Characterization of Secreted Biomolecules i...
Pires, Rita; Rodrigues, Lénia; Santos, Fátima; Duarte, Iola; Ciordia, Sérgio; Peixe, Augusto; Cardoso, HéliaSomatic embryogenesis (SE) involves the formation of embryo-like structures from somatic cells without fertilization and is widely used for clonal propagation and genetic transformation. However, in olive (Olea europaea sp. europaea), SE remains challenging due to the recalcitrant behavior of adult tissues when used as initial explants. Bioactive molecules released into the culture medium (conditioned medium, C...
Unraveling somatic embryogenesis signaling pathways – the role of extracellular...
Pires, Rita; Peixe, Augusto; Santos, Fátima; Cardoso, HéliaSomatic embryogenesis (SE) can be described as a process involving the formation of structures similar to the zygotic embryos, arising from dedifferentiation of somatic cells and not requiring the occurrence of fertilization. This process, widely used in clonal propagation and genetic transformation of several plant species, is not routinely used in olive (Olea europaea sp. europaea L.), due to the recalcitrant...
Efeitos da fisioterapia na função pélvica e qualidade de vida em mulheres co...
Matos, Elisabete; Pires, T; Santos, Fátima; Pires, Patrícia Maria Rodrigues Pereira; Viana, Sara; Viana, RuiIn recent years, pelvic floor physiotherapy, namely pelvic floor muscle training (PFMT) has shown a high importance in women with urinary incontinence (UI), optimizing pelvic function and quality of life (QoL). Objective: Evaluate the effects of pelvic floor physiotherapy on pelvic function and QoL in women with UI. Methods: Computerized search in the databases Pubmed, Scopus, and Web of Science, using the comb...
Efeitos motores da eletroestimulação transcraniana por corrente contínua associ...
Horing, Maria Julia Oliveira Caldeira; Festas, Clarinda; Viana, Rui; Santos, Fátima; Santos, Ana Filipa; Santos, Ana FilipaA paralisia cerebral (PC) é uma das causas mais frequente de disfunções motoras, cognitivas, comunicativas e comportamentais em crianças, originando limitações nas suas vidas. A eletroestimulação transcraniana por corrente contínua (tDCS) é uma técnica nãoinvasiva que emprega uma corrente elétrica de baixa intensidade para modulação dos neurônios cerebraise pode ser aliada a fisioterapia.O objetivoda pesquisa f...
Normative values and reference equations of the 4-meter gait speed test for Por...
Silva, Sara; Vilarinho, Rui; Festas, Clarinda; Santos, Fátima; Montes, António Mesquita; Jácome, Cristina; Mesquita Montes, António; Vilarinho, RuiTo determine the normative values and reference equations of the 4-Meter Gait Speed Test (4MGS) at usual and maximal speed for Portuguese adults. We also assessed the participant experience during the performance of the 4MGS. A cross-sectional study was conducted with individuals without disabilities. Sociodemographic, anthropometric, smoking habits and physical activity (Brief Physical Activity Assessment Tool...
Transcriptomic analysis and epigenetic regulators in human oocytes at different...
Caniçais, Carla; Sobral, Daniel; Vasconcelos, Sara; Cunha, Mariana; Pinto, Alice; Guimarães, Joana Mesquita; Santos, Fátima; Barros, AlbertoHuman oocytes are highly specialized cells with the capacity to store and regulate mRNAs during oocyte maturation, in preparation for post-fertilization steps. Here we performed single-oocyte transcriptomic analysis of human oocytes in three meitoic maturation stages - Germinal Vesicle (GV; n = 6), Metaphase I (MI; n = 6) and Metaphase II (MII; n = 7). Single-oocyte transcriptomic analysis revealed that the tot...
An atypical presentation of pediatric malignant spinal cord compression
Gaia, Maria João; Lopes, Vilma; Tenente, Joana; Coelho, Janine; Vila Real, Marta; Santos, FátimaBackground: Malignant spinal cord compression (MSCC) is a rare but serious complication of pediatric malignancies that can result in permanent neurologic deficits. The prognosis depends on neurological symptoms at diagnosis. Case report: A nine-year-old girl was evaluated for worsening pain in the left anterior iliac spine with one month of evolution. Over the next two days, she showed progressive gait instabil...
Pelizaeus-Merzbacher Disease: A Rare Cause of Nystagmus and Developmental Delay
Alba, Diana; Araújo, André; Geraldo, Ana Filipa; Rangel, Maria Adriana; Vila Real, Marta; Santos, FátimaPelizaeus-Merzbacher disease (PMD) is an X-linked leukodystrophy of the central nervous system characterized by a developmental arrest in myelin formation. It is classified into five phenotypes, with different severity. The most common clinical features are nystagmus, spasticity, tremor, ataxia, and hypotonia. A 11-month-old child was referred to the Neuropediatric Unit due to nystagmus, hypotonia, and developm...
An atypical presentation of pediatric malignant spinal cord compression
Gaia, Maria João; Lopes, Vilma; Tenente, Joana; Coelho, Janine; Real, Marta Vila; Santos, FátimaBackground: Malignant spinal cord compression (MSCC) is a rare but serious complication of pediatric malignancies that can result in permanent neurologic deficits. The prognosis depends on neurological symptoms at diagnosis. Case report: A nine-year-old girl was evaluated for worsening pain in the left anterior iliac spine with one month of evolution. Over the next two days, she showed progressive gait instabil...