This work was supported by Decit, SCTIE, Brazilian Ministry of Health, Conselho Nacional de Desenvolvimento Cient?fico - CNPq (440685/ 2016-8, 440856/2016-7 and 421598/2018-2), Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES - (88887.130716/2016-00), European Union?s Horizon 2020 Research and Innovation Programme under ZIKAlliance Grant Agreement (734548), STARBIOS (709517), Funda??o de Ampa...
We conducted the genome sequencing and analysis of the first confirmed COVID-19 infections in Brazil. Rapid sequencing coupled with phylogenetic analyses in the context of travel history corroborate multiple independent importations from Italy and local spread during the initial stage of COVID-19 transmission in Brazil.