9 documents found, page 1 of 1
Estudo farmacológico de 1,8-Cineol, um óxido terpênico presente em óleos essenc...
Santos, Flávia Almeida1,8-cmeole (cineole), a terpene compound present in various essential oils of plants that belong to Eucalyptus, Rosemary and Psidium species was investigated for its local and systemic pharmacological effects in rats and mice. In the evaluation of local effects, we verified its capacity to induce inflammatory edema and local nociception following the subplantar injection and as well the pharmacological characte...
Cashew apple fiber prevents high fat diet-induced obesity in mice: an NMR metab...
Carvalho, Diana Valesca; Silva, Lorena Mara Alexandre; Alves Filho, Elenilson Godoy; Santos, Flávia Almeida; Lima, Renan Pereira deDietary fiber intake plays an important role in the prevention of obesity. This study aimed at investigating the effect of cashew fiber without low molecular weight compounds (CABwc) on obesity prevention and metabolomics in a murine model of diet-induced obesity. Mice were fed a chow diet (CD), a high-fat diet (HFD) or a high-fat diet supplemented with CABwc (10%) (HFD-CABwc) for 15 weeks. The body weight, abd...
Hyptis suaveolens (L.) Poit protects colon from TNBS-induced inflammation via i...
Machado, Flávia Danniele Frota; Formiga, Rodrigo de Oliveira; Lima, Gedson Rodrigues de Morais; de Jesus, Neyres Zínia TaveiraMade available in DSpace on 2021-06-25T11:05:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-30; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Ethnopharmacological relevance: In folk medicine Hyptis suaveolens (Lamiaceae) has been reported to relieve respiratory and gastrointestinal infections, indigestion, cold, pain, fever, cramps, skin diseases, gastric ulcer and inflamma...
The triterpenoid alpha, beta-amyrin prevents the impaired aortic vascular react...
Santos, Flávia Almeida; Batista-Lima, Francisco José; Nunes, Paulo Iury Gomes; Viana, Ana Flávia Seraine CustódioTo characterize the pro tective effects of the triterpenoid mixture alpha, beta-amyrin (AMY, 20 mg/kg, during 15 days) on the reactivity of isolated aorta of high- fat diet (HFD)-induced obese mice. Male Swiss mice were fed with HFD or normal diet (ND) for 15 weeks. Contractions of thoracic aorta in response to KCl or phen- ylephrine (PHE) and relaxation by acetylcholine (ACh) or sodium nitroprusside (SNP) were...
The resin from protium heptaphyllum prevents high-fat diet-induced obesity in m...
Carvalho, Karine Maria Martins Bezerra; MarinhoFilho, José Delano Barreto; Melo, Tiago Sousa de; Araújo, Ana Jérsia; Quetz, Josiane da SilvaHerbal compounds rich in triterpenes are well known to regulate glucose and lipid metabolism and to have beneficial effects on metabolicdisorders.ThepresentstudyinvestigatedtheantiobesitypropertiesofresinfromProtiumheptaphyllum(RPH)andthe possible mechanisms in mice fed a high-fat diet (HFD) for 15 weeks. Mice treated with RPH showed decreases in body weight, netenergyintake,abdominalfataccumulation,plasmagluco...
Oleanolic Acid, a Pentacyclic Triterpene Attenuates the Mustard Oil-Induced Col...
David, Juceni Pereira de Lima; David, Jorge Mauricio; Lima Júnior, Roberto César Pereira; Santos, Flávia Almeida; Maia, Juliana LemosTexto completo: acesso restrito.p.82-85; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-09-05T15:01:39Z No. of bitstreams: 1 _pdf.pdf: 202301 bytes, checksum: 96cc86d2f165688f542988affee41d78 (MD5); Approved for entry into archive by Alda Lima da Silva(sivalda@ufba.br) on 2013-09-16T19:52:54Z (GMT) No. of bitstreams: 1 _pdf.pdf: 202301 bytes, checksum: 96cc86d2f165688f542988affee41d78 (MD5); Made ...
Topical anti-inflammatory potential of Physalin E from Physalis angulata on exp...
Pinto, Natália Bitú; Morais, Talita Cavalcante; Carvalho, Karine Maria Martins Bezerra; Silva, Cecília Rocha; Andrade, Geanne Matos deThe anti-inflammatory effect of physalin E, a seco-steroid isolated from Physalis angulata L. was evaluated on acute and chronic models of dermatitis induced by 12-O-tetradecanoyl-phorbol-13- acetate (TPA) and oxazolone, respectively, in mouse ear. The changes in ear edema/thickness, production of pro-inflammatory cytokines (TNF- a and IFN- g ), myeloperoxidase (MPO) activity, and histological and immunohistoch...
Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice in...
Morais, Talita Cavalcante; Lopes, Synara Cavalcante; Carvalho, Karine Maria Martins Bezerra; Arruda, Bruno Rodrigues; Souza, Francisco Thiago Correia deAIM: To investigate the effects of mangiferin on gas - trointestinal transit (GIT) in normal and constipated mice, together with the possible mechanism. METHODS: Intragastrically-administered charcoal mea was used to measure GIT in overnight starved Swiss mice. In the first experiments, mangiferin (3 mg/kg, 10 mg/kg, 30 mg/kg, and 100 mg/kg, po ) or tegaserod (1 mg/kg, ip ) were administered 30 min before the c...
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nocicepti...
Maia, Juliana Lemos; Lima Júnior, Roberto César Pereira; Melo, Caroline Mourão; David, Juceni Pereira de Lima; David, Jorge MauricioRESTRITO; Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2012-07-10T14:48:21Z No. of bitstreams: 1 DD.pdf: 191921 bytes, checksum: e7e0d97358e281aeda5710f62c757522 (MD5); Made available in DSpace on 2012-07-10T14:48:21Z (GMT). No. of bitstreams: 1 DD.pdf: 191921 bytes, checksum: e7e0d97358e281aeda5710f62c757522 (MD5) Previous issue date: 2006; The anti-inflammatory pentacyclic triterpene, oleanoli...