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Cognitive impairment in prostate cancer patients receiving androgen deprivation...

Barreira, João Vasco; Barreira, Pedro; Falcão, Gil; Garcez, Daniela; Silva, Pedro; Santos, Gustavo; Fontes-Sousa, Mário; Mendes, José Leão; Reis, Filipa

Background: Androgen deprivation therapy (ADT) is a primary treatment for prostate cancer (PCa) that effectively reduces androgen levels to suppress tumor progression. However, growing evidence suggests potential cognitive side effects, raising concerns about the long-term neurological consequences of this treatment. Objective: This scoping review aims to synthesize the existing evidence linking ADT to cognitiv...



Queer representation incorporated at “Him”, character of “The Powerpuff Girls"

Santos, Gustavo; Mancio, Camila Peres; Maranho, Elisa

In audiovisual's history, minorities as LGBTQ+ people had been excluded or stereotyped, thus, this study has as a guiding question understanding “Him”, character of the classic cartoon series “The Powerpuff Girls”, produced between 1998 and 2005 by Cartoon Network - by the bias of the Queer Theory, which address the questions about non-heteronormative bodies that belong to marginalized groups whose rights are d...


Do improved pastures affect enzymatic activity and C and N dynamics in soils of...

Rodrigues, Ana Raquel; Silva, Emanuelle; Santos, Gustavo; Coutinho, João; Madeira, Manuel

Vast montado areas are threatened by degradation, as the result of a long history of land use changes. Since improved pastures have been installed aiming soil quality improvement and system sustainability, it is crucial to evaluate the effects of these management changes on soil organic matter status and soil biological activity, as soil quality indicators. Therefore, a 35-yr old improved pasture and a natural ...

Date: 2019   |   Origin: Revista de Ciências Agrárias


A SUPREMACIA SERÁ SEMPRE DOS MAIS INTELIGENTES”: A FORMAÇÃO JURÍDICA PAULISTA N...

Santos, Gustavo; Mesquita, Ilka Miglio

O presente artigo objetiva identificar o processo de constituição da cultura jurídica pela formação dos bacharéis da Academia de Direito de São Paulo, no século XIX, a partir das memórias publicadas por Vampré (1977) e Nogueira (1977), da Lei de 11/08/1827, do Estatuto de Couto Ferraz (1854) e do Estatuto de Leôncio de Carvalho (1879). Indagamos: Como o curso foi organizado? Para que, para quem e o que se objet...

Date: 2018   |   Origin: Oasisbr

Deciphering the role of exposed surface residues in protein stability

Pacheco, Ana Margarida; Barroca, Mário Jorge Faria; Oliveira, Bruno; Veloso, Paulo; Santos, Gustavo; Collins, Tony

[Excerpt] Xylanases (EC 3.2.1.8) are glycoside hydrolase enzymes which breakdown the β-1,4 linkages of xylan, one of the most abundant polysaccharide in the cell wall of plants. Xylanases are important industrial enzymes with application in the food, feed and industrial enzymes markets. pXyl is an industrially important psychrophilic family 8 xylanase which is already being commercialized worldwide for baking a...


Deciphering the factors defining the pH-dependence of a commercial glycoside hy...

Barroca, Mário Jorge Faria; Santos, Gustavo; Johansson, Björn; Gillotin, Florian; Feller, Georges; Collins, Tony

A prerequisite to the use of any enzyme in any industrial process is an understanding of its activity and stability under process conditions. Glycoside hydrolase family 8 enzymes include many important biotechnological biocatalysts yet little is known of the performance of these with respect to pH. A better understanding of this parameter and its relationship to structure and function in these enzymes will allo...


Do improved pastures affect enzymatic activity and C and N dynamics in soils of...

Rodrigues, Ana Raquel; Silva, Emanuelle; Santos, Gustavo; Coutinho, João; Madeira, Manuel

Vast montado areas are threatened by degradation, as the result of a long history of land use changes. Since improved pastures have been installed aiming soil quality improvement and system sustainability, it is crucial to evaluate the effects of these management changes on soil organic matter status and soil biological activity, as soil quality indicators. Therefore, a 35-yr old improved pasture and a natural ...


From conditional compilation to aspects: a case study in software product lines...

Alves, Vander; Costa Neto, Alberto; Soares, Sérgio; Santos, Gustavo; Calheiros, Fernando; Nepomuceno, Vilmar; Pires, Davi; Leal, Jorge; Borba, Paulo

Apart from adoption strategies, an existing Software Product Line (SPL) implemented using some variability mechanisms can be migrated to use another variability mechanism. In this paper, we present some migration strategies from one SPL implemented with conditional compilation to one using Aspect-Oriented Programming (AOP). The strategies present a variability pattern handled by the first mechanism and shows ho...

Date: 2013   |   Origin: Oasisbr

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