804 documents found, page 1 of 81
Sobreiro: Participation and intervention of local communities in the historical...
Roberti, Ana Clara Nunes; Santos, Helena; Brandão, DanielThis paper intends to discuss a collaborative initiative, carried out within the scope of a doctoral scientific research in the field of Arts and Design and an institution that supports socio-economically vulnerable communities. The work took place in the Sobreiro Social Housing, located in the city of Maia, in Portugal, home to more than 600 families. By using methodologies specific to arts and cultural studie...
The dialectical relationship between the authorial and the collaborative in con...
Roberti, Ana Clara Nunes; Santos, Helena; Brandão, DanielThis article discusses the intersections between authorial and collaborative work in the scope of ethnographic documentary departing from three case studies: two research projects and one citizen collective of participatory media. All case studies were developed in Porto, Portugal, between 2013 and 2020, focusing on the city’s invisibilities and everyday experiences, searching for alternative narratives to the ...
From intimacy to urban landscape: Images of the transformations of the Rainha D...
Roberti, Ana Clara Nunes; Santos, Helena; Brandão, DanielThe present communication proposes an imagery study on the transformations of the social housing Rainha Dona Leonor, in Porto, rehabilitated between 2017 and 2019. Through an immersive ethnographic work, it was possible to closely follow the radical changes that took place, from the demolition of the five housing blocks to the construction of a single block. In short, our methodology was guided by the following...
The ethnographic film as a way of thinking: Responsibilities of the encounter w...
Roberti, Ana Clara Nunes; Santos, Helena; Brandão, DanielThis paper addresses the ethical encounter between the filmmaker/researcher and the subject in the scope of ethnographic film, reinforcing its importance as an artistic and scientific field capable of dealing with places and people in situations of identity and social risk. The basis for the discussion is the research project Island City (Roberti 2020), which studied and documented deeply embedded and socioecon...
Predictors of Secukinumab Treatment Response and Continuation in Axial Spondylo...
Pons, Marion; Georgiadis, Stylianos; Hetland, Merete Lund; Ahmadzay, Zohra Faizy; Rasmussen, Simon; Christiansen, Sara N.; Di Giuseppe, DanielaPublisher Copyright: © 2025 The Journal of Rheumatology.; Objective. In patients with axial spondyloarthritis (axSpA) initiating secukinumab (SEC), we aimed to identify baseline (treatment start) predictors of achieving low disease activity (LDA) after 6 months, as measured by the Axial Spondyloarthritis Disease Activity Score using C-reactive protein (ASDAS-CRP) and Bath Ankylosing Spondylitis Disease Activity...
Sociodemographic factors and biologic therapy exposure impacting health-related...
Santos, Helena; Oliveira Henriques, Ana Rita; Canhão, Helena; Machado, Pedro M.; M. Pimentel-Santos, F.; Silva, Cândida; Lobão, BárbaraFunding Information: This work was supported by a research grant from the Portuguese Society of Rheumatology. Publisher Copyright: © The Author(s) 2025.; Psoriatic arthritis (PsA) is a very heterogeneous disease with significant impact on health-related quality-of-life (HRQoL). Our objective was to assess and identify predictors of HRQoL in a 3-year follow-up period among PsA patients. Patients with PsA include...
Biologic disease-modifying antirheumatic drugs survival in late-onset axial spo...
Silva, Susana P.; Monteiro, Beatriz; Oliveira, Cláudia Pinto; Costa, Roberto Pereira da; Matos, Carolina Ochôa; Lopes, Mariana DizObjectives Although axial spondyloarthritis (axSpA) typically begins before age 45, late-onset axSpA (lo-axSpA) has been widely recognized. While existing literature describes this subgroup, data on therapeutic approaches remain limited. Therefore, we aimed to evaluate the efficacy and safety of biologic DMARDs in patients with lo-axSpA.Methods We conducted a retrospective, multicentre, national cohort study us...
Long-term predictors of health-related quality of life in spondyloarthritis
Santos, HelenaIntroduction Spondyloarthritis (SpA) is a group of inflammatory rheumatic diseases that share common clinical features, genetic susceptibility, and pathophysiological mechanisms. It includes ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis associated with inflammatory bowel disease, and undifferentiated SpA. Recently, SpA has also been classified into axial SpA (axSpA) and peripheral S...
Doenças mitocondriais na era da sequenciação de nova geração: estudo de 450 doe...
Nogueira, Célia; Pereira, Cristina; Silva, Lisbeth; Laranjeira, Mateus; Lopes, Altina; Neiva, Raquel; Rodrigues, Esmeralda; Campos, TeresaAs doenças mitocondriais (DM) são doenças raras, clínica e geneticamente heterogéneas, de difícil diagnóstico, para as quais não existe uma terapia eficaz. O desenvolvimento da tecnologia de sequenciação de nova geração (NGS) revolucionou o diagnóstico molecular deste grupo de doenças, permitindo a identificação de novos genes associados a estas patologias. Nesta nova era genética, através da utilização da tecn...
Remodelling of grape cell wall upon infection with biotrophic and necrotrophic ...
Santos, HelenaGrapes are fruits highly susceptible to various diseases and stresses, including powdery mildew, esca disease, and grey mould. These conditions significantly impact grape quality, yield production, and aroma profiles. The infection strategy by the biotrophic fungus Erysiphe necator prioritises the development of appressoria for cell penetration of photosynthetic tissues using mechanical force, while the hemibio...