4 documents found, page 1 of 1
Epidemiological distribution and evolutionary profile of mayaro virus in the am...
Marinho, Mikaela dos Santos; Ferreira, Giulia Magalhães; Santos, Igor Andrade; Grosche, Victoria Riquena; Jardim, Ana Carolina GomesTrabalho de Conclusão de Curso (Graduação); 2023-06-10; Mayaro virus (MAYV) is the etiologic agent of Mayaro Fever, a disease characterized by dengue-like symptoms and arthralgias that can progress to a chronic condition. MAYV is phylogenetically classified into the genotypes D (widely dispersed), L (limited), and N (new), being the D the most common. Additionally, a new genotype was generated by a recombinatio...
Insights on the sars-cov-2 genome variability: The lesson learned in brazil and...
Grosche, Victória Riquena [UNESP]; Santos, Igor Andrade; Ferreira, Giulia Magalhães; Dutra, João Victor Rodrigues; Costa, Larissa CatharinaMade available in DSpace on 2022-04-28T19:47:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Since the beginning of the SARS-CoV-2 spread in Brazil, few studies have been published analysing the variability of viral genome. Herein, we described the dynamic o...
Repurposing potential of rimantadine hydrochloride and development of a promisi...
Santos, Igor Andrade; Pereira, Anna Karla dos Santos; Guevara-Vega, Marco; de Paiva, Raphael Enoque Ferraz; Sabino-Silva, RobinsonMade available in DSpace on 2022-04-28T19:48:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Most of the patients infected with Chikungunya virus (CHIKV) develop chronic manifestations characterized by pain and deformity in joints, impacting their quality of life. The aminoadamantanes, in their turn, have been exploited due to their biological activities, with amantadine and memantine recently ...
Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from...
Santos, Igor Andrade; Shimizu, Jacqueline Farinha [UNESP]; de Oliveira, Débora Moraes; Martins, Daniel Oliveira Silva [UNESP]; Cardoso-Sousa, LéiaMade available in DSpace on 2021-06-25T11:03:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies. In this context, snake venom proteins have demonstrated antiviral activity against...