11 documents found, page 1 of 2

Cutaneous Metastasis in Advanced Gastric Cancer

N/A; N/A

Cutaneous Metastasis in Advanced Gastric Cancer.

DNA damage independent inhibition of NF-κB transcription by anthracyclines

Anthracyclines are among the most used and effective anticancer drugs. Their activity has been attributed to DNA double-strand breaks resulting from topoisomerase II poisoning and to eviction of histones from select sites in the genome. Here, we show that the extensively used anthracyclines Doxorubicin, Daunorubicin, and Epirubicin decrease the transcription of nuclear factor kappa B (NF-κB)-dependent gene targ...

GASTRIC CANCER D2 LAPAROSCOPIC LYMPHADENECTOMY OF 8-12TH STATIONS

Defining clinical conditions in long-term healthcare as a first step to impleme...

Background Increasing healthcare costs is a concern of all developed countries. In Long-Term Healthcare (LTH) this is reinforced by population ageing and corresponding prevalence of chronic diseases. Thus, it is fundamental to accurately measure costs and outcomes in healthcare, improving value created for patients, i.e., patient centred health outcomes per monetary unit of cost [1, 2]. TDABC methodology applie...

Time-driven activity based costing (TDABC) in long-term healthcare (LTH)-A prac...

Statement of the Problem: This paper focuses the cost component of a larger ongoing action-research project (CARE4VALUE), aiming to enhance value creation (patient-centered health outcomes per unit of cost) in LTH providers. The main objective is to share the experience of designing and implementing TDABC in a Portuguese LTH unit. TDABC methodology applied to healthcare allows identifying the cost per patient, ...

Defining clinical conditions in long-term healthcare as a first step to impleme...

Background Increasing healthcare costs is a concern of all developed countries. In Long-Term Healthcare (LTH) this is reinforced by population ageing and corresponding prevalence of chronic diseases. Thus, it is fundamental to accurately measure costs and outcomes in healthcare, improving value created for patients, i.e., patientcentred health outcomes per monetary unit of cost [1, 2]. TDABC methodology applied...

Sepsis: the need for tolerance not complacency

Sepsis is a life-threatening condition that arises as a systemic inflammatory response syndrome to an infection. Its uncontrolled progression can in frequent cases lead to multiple organ failure, which is still associated with high mortality rates. Modern antibiotics made clear that the infection is only an initiating, and not always necessary, event of this syndrome as many patients with sepsis die despite eff...

PRE-TREATMENT OF THE DONOR WITH ERYTHROPOIETIN AND TREATMENT OF THE RECIPIENT W...

The effect of 5-aminoisoquinolinone during machine perfusion of kidneys recover...