167 documents found, page 1 of 17
A transformação dos votos em mandatos: O sistema eleitoral português em análise
Santos, JoãoA comemoração dos 50 anos da Revolução de Abril tem sido favorável à realização de uma série de balanços relativos aos elementos definidores da democracia portuguesa. Neste sentido, o presente Working Paper carateriza o sistema eleitoral português e avalia a performance do mesmo ao longo do seu quase meio século de existência. O desempenho do sistema eleitoral foi medido através da definição de três critérios-c...
PLGA nanoparticles double-decorated with a TAT peptide and folic acid to target...
Andrade, Stéphanie; Ramalho, Maria J.; Santos, João; Santos, Sílvio Roberto Branco; Melo, Luís Daniel Rodrigues; Guimarães, Nuno; Ferraz, Maria P.Treating bacterial infections has become increasingly difficult due to the rise in antibiotic-resistant bacterial strains. Strategies involving the targeted delivery of antibiotics have been proposed to minimize the administered antibiotic doses. This study aims to develop the first double-modified nanovehicle capable of increasing bacterial membranes permeability while specifically targeting Staphylococcus aur...
Five decades of groundwater change across a diverse Mediterranean climate regio...
Costa, Diogo; Santos, João; Chambel, AntónioGroundwater systems in Mediterranean regions are under increasing pressure from climate variability and human activities, yet long-term, large-scale assessments of water quality dynamics remain scarce. This study compiles and analyses over 4.4 million observations collected from 2,501 monitoring stations across Portugal, covering an area of 89,015 km2 over a 3.5-decade period (1970–2024), and encompassing 15 na...
Aprendizagem de limites e continuidade em funções de uma variável real: um olha...
Santos, João; Oliveira, Naralina; Santos, MarcílioEste artigo se refere a um estudo de conclusão de curso, que trata sobre os obstáculos epistemológicos revelados na aprendizagem de limites e continuidade de funções de uma variável real. Observamos, na perspetiva de Rezende (2003), Bachelard (1996) e Brousseau (1983), que algumas dualidades essenciais presentes no desenvolvimento do Cálculo Diferencial e Integral podem estar relacionadas com a resistência de u...
Cover crops effect on floristic community and yield of maize
Santos, João; Grifo, Anabela; Amaral, Artur; Calha, IsabelInnovative methods of weed management, such as cover crops, are becoming increasingly necessary. However, despite the objectives set out in the European Green Deal, their adoption by farmers has been gradual, regardless of the advantages they offer in terms of maintaining soil organic matter, preventing erosion and, in particular, reducing the abundance and biomass of weeds. In order to assess the impact of mix...
Water quality assessment of a hydro-agricultural reservoir in a Mediterranean R...
Catarino, Adriana; Martins, Inês; Mourinha, Clarisse; Santos, João; Anastácio, Pedro; Tomaz, Alexandra; Palma, PatríciaIn regions where drought has become a common occurrence for most of the year and where agriculture is the main economic activity, the development of hydro-agricultural systems has made it possible to improve water management. Despite this, the intensification of agriculture combined with climate change leads to a potential decrease in water quality and water management practices are essential to improve agro-en...
Abaladiça - Exposição do Ano - ESAD.CR - Exhibition of the year 2024
Macedo, Miguel; Cardoso, Carla M; Afonso, Lígia; Santos, JoãoPartindo do regionalismo alentejano, “abaladiça” era a última bebida que se tomava antes de sair de um bar ou de um a festa. Uma para o caminho, consumida na despedida, marca um momento especial: a derradeira ronda de um percurso, seja este um regresso a casa ou o início de uma nova jornada. ABALADIÇA, a exposição dos finalistas da ESAD.CR em 2024, foi uma imersão na longa partilha realizada entre estudantes do...
Disease similarity network analysis of Autism Spectrum Disorder and comorbid br...
Vilela, Joana; Martiniano, Hugo; Marques, Ana Rita; Santos, João; Rasga, Célia; Oliveira, Guiomar; Vicente, Astrid MouraBackground/Objectives: Autism Spectrum Disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder , with variable severity and multiple comorbidities. Given the previous evidence of genetic overlap between ASD and several comorbid brain disorders, we sought to explore the genetic similarity with ASD across a range of brain disorders, using a genetic similarity disease network approach. Methods: We...
Effectiveness of synchronous non-class education in higher health education
Ferreira, António; Santos, catarina; Santos, João; Figueiredo, Marta; Ratushnyi, RomanBackground: the SARS-COV2 pandemic has conditioned the functioning of Higher Education Institutions, leading to the adoption of measures to ensure the teaching process, until then face-to-face, towards a synchronous non-face-to-face teaching typology. Objective: to evaluate the effectiveness of synchronous remote teaching in higher health education in response to the pandemic, from the student's perspective, an...
Enhancing the longevity and functionality of Ti-Ag dry electrodes for remote bi...
Carvalho, Daniel; Marques, Sandra Mariana Silva; Siqueira, Giorgia; Ferreira, Armando José Barros; Santos, João; Geraldo, DulceThis study aims to evaluate the lifespan of Ti-Ag dry electrodes prepared using flexible polytetrafluoroethylene (PTFE) substrates. Following previous studies, the electrodes were designed to be integrated into wearables for remote electromyography (EMG) monitoring and electrical stimulation (FES) therapy. Four types of Ti-Ag electrodes were prepared by DC magnetron sputtering, using a pure-Ti target doped with...