13 documents found, page 1 of 2
Prognosticating the Outcome of Intensive Care in Older Patients - a Narrative R...
Beil, M; Moreno, R; Fronczek, J; Kogan, Y; Moreno, R; Flaatten, H; Guidet, B; de Lange, D; Leaver, S; Nachshon, A; van Heerden, P; Joskowicz, LPrognosis determines major decisions regarding treatment for critically ill patients. Statistical models have been developed to predict the probability of survival and other outcomes of intensive care. Although they were trained on the characteristics of large patient cohorts, they often do not represent very old patients (age ≥ 80 years) appropriately. Moreover, the heterogeneity within this particular group i...
The Sequential Organ Failure Assessment (SOFA) Score: Has the Time Come for an ...
Moreno, R; Rhodes, A; Piquilloud, L; Hernandez, G; Takala, J; Gershengorn, H; Tavares, M; Coopersmith, C; Myatra, S; Singer, M; Rezende, E; Prescott, HThe Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. Changes in clinical practice over the last few decades, with new interventions and a greater focus on non-invasive monitoring systems, mean it is time to update the SOFA score. As a first step in this process, we propose so...
Association of Chronic Heart Failure with Mortality in Old Intensive Care Patie...
Romano Bruno, R; Wernly, B; Wolff, G; Fjølner, J; Artigas, A; Bollen Pinto, B; Schefold, J; Kindgen‐Milles, D; Baldia, P; Kelm, M; Beil, M; Sviri, SAims: Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID-19). This prospective international multicentre study investigates the role of pre-existing CHF on clinical outcomes of critically ill old (≥70 years) intensive care patients with COVID-19. Methods and results: Patients with pre-existing CHF were subclassified as having ischaemic or non-ischaemic cardiac di...
Increased 30-Day Mortality in Very Old ICU Patients with COVID-19 Compared to P...
Guidet, B; Jung, C; Flaatten, H; Fjølner, J; Artigas, A; Bollen Pinto, B; Schefold, J; Beil, M; Sigal, S; Vernon van Heerden, P; Szczeklik, WPurpose: The number of patients ≥ 80 years admitted into critical care is increasing. Coronavirus disease 2019 (COVID-19) added another challenge for clinical decisions for both admission and limitation of life-sustaining treatments (LLST). We aimed to compare the characteristics and mortality of very old critically ill patients with or without COVID-19 with a focus on LLST. Methods: Patients 80 years or older ...
The Impact of Frailty on Survival in Elderly Intensive Care Patients with COVID...
Jung, C; Flaatten, H; Fjolner, J; Bruno, R; Wernly, B; Artigas, A; Pinto, B; Schefold, J; Wolff, G; Kelm, M; Beil, M; Sviri, S; Heerden, P; Szczeklil, WBackground: The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in patients with COVID-19 is frailty. The degree of frailty could be used to assist both the triage into intensive care, and decisions regarding treatment limitations. Our study sought to determine th...
Sepsis at ICU Admission Does Not Decrease 30-Day Survival in Very Old Patients:...
Ibarz, M; Boumendil, A; Haas, L; Irazabal, M; Flaatten, H; de Lange, D; Morandi, A; Andersen, F; Bertolini, G; Cecconi, M; Christensen, S; Faraldi, LBackground: The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Sepsis incidence has risen in recent years and identification of outcomes is of considerable public importance. We aimed to determine whether VIPs admitted for sepsis had different outcomes than ...
The Contribution of Frailty, Cognition, Activity of Daily Life and Comorbiditie...
Guidet, B; de Lange, DW; Boumendil, A; Leaver, S; Watson, X; Boulanger, C; Szczeklik, W; Artigas, A; Morandi, A; Andersen, F; Zafeiridis, T; Jung, CPurpose: Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival after ICU admission. The primary aim of this study was to describe the prevalence of frailty, cognition decline and activity of daily life in addition to the presence of comorbidity and polypharm...
Sex-Specific Outcome Disparities in Very Old Patients Admitted to Intensive Car...
Wernly, B; Romano Bruno, R; Kelm, M; Boumendil, A; Morandi, A; Andersen, F; Artigas, A; Finazzi, S; Cecconi, M; Christensen, S; Faraldi, LFemale and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and predictors of mortality. In total, 7555 patients were included in this analysis, 3973 (53%) male and 3582 (47%) female patients. The primary endpoint was 30-day-mortality. Baseline characteristics...
A Comparison of Very Old Patients Admitted to Intensive Care Unit After Acute V...
Jung, C; Wernly, B; Muessig, J; Kelm, M; Boumendil, A; Morandi, A; Andersen, F; Artigas, A; Bertolini, G; Cecconi, M; Christensen, S; Faraldi, LBackground: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (≥80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed. Methods: In total, 5063 VIPs were included in this analysis, 922 were admitted after elective surgery or intervention, 4141 acut...
The Contribution of Frailty, Cognition, Activity of Daily Life and Comorbiditie...
Guidet, B; de Lange, D; Boumendil, A; Leaver, S; Watson, X; Boulanger, C; Szczeklik, W; Artigas, A; Morandi, A; Andersen, F; Zafeiridis, T; Jung, CPurpose: Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival after ICU admission. The primary aim of this study was to describe the prevalence of frailty, cognition decline and activity of daily life in addition to the presence of comorbidity and polypharm...